Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Neutrogena® On-the-Spot® Acne Treatment

BY NEUTROGENA

4.0 out of 5 stars
  • 5 Stars45%
  • 4 Stars27%
  • 3 Stars17%
  • 2 Stars7%
  • 1 Star4%
4.02 / 5 based on 2,799 Reviews

Description

Benefits:

Some acne spot treatments contain high doses of the acne medication Benzoyl Peroxide, which can irritate skin. It can also cause redness and dryness, which can make acne worse. Our formula contains just 2.5% Benzoyl Peroxide, yet is clinically proven to be so effective that skin starts getting clearer on day 1 – all without over-drying, stinging or burning skin.

This fast working formula is so lightweight that it quickly absorbs into skin. And it goes deep down to the pores to kill the acne bacteria that cause pimples and helps to prevent new ones from forming.

  • Oil-free
  • Non-comoedogenic (won't clog pores)
  • 2.5% Benzoyl Peroxide

How To Use :

  • Clean the skin thoroughly before applying this product.
  • Cover the entire affected area with a thin layer one to three times daily.
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor.
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
  • If going outside, apply sunscreen after using this product.
  • If irritation or sensitivity develops, stop use of both products and ask a doctor.

Active ingredient:

Benzoyl Peroxide 2.5% (Acne Medication).

Inactive ingredients :

Water, Carbomer Homopolymer type B, Ethylhexylglycerin, Sodium Hydroxide, Chlorphenesin, Disodium EDTA, Laureth-4, Hydroxypropyl Methylcellulose.

Purpose : Acne Medication

Use
For the treatment of acne.

Warnings:

For external use only
When using this product
skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
Do not use if you
have very sensitive skin
are sensitive to benzoyl peroxide.
When using this product
avoid unnecessary sun exposure and use a sunscreen.
avoid contact with the eyes, lips and mouth.
avoid contact with hair or dyed fabrics, which may be bleached by this product.
skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
Stop use and ask a doctor if
irritation becomes severe.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions:

Clean the skin thoroughly before applying this product. Cover the entire affected area with a thin layer one to three times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Other information: Store at 20°C-25°C (68°F-77°F).

see more...

Top Questions See all 357 Q&A

  • Can you use this on blackheads?2 Answers
  • How well does this work on oily/dry skin? Because some da...4 Answers
  • I've always had pimples here and there on my face and I'm...4 Answers
Neutrogena® On-the-Spot® Acne Treatment
Neutrogena® On-the-Spot® Acne Treatment
Reviews (2799)
Q&A (140)
Media (54)
Buy on Amazon
REVIEWS
Mallory M.
Oak Hill, WV
107 reviews
Beauty Junkie Expert Level 2
I have struggled with acne since I was 14 so I am desperate to find any product that will help my skin. My full face acne will only go away when I use Accutane but I hoped this spot treatment would help reduce the size of my pimples. My skin is very dry and sensitive and luckily this product did not have any reaction to my skin. I apply this at night to my face and have not noticed any changes at all. No size reduction, no clearing up, nothing. This might work for people that get the occasional zit and respond well to other acne creams like this. People with full face acne that is stubborn should get prescription creams.

This product will also bleach out your bed sheets, clothing, and even your hair if it is dyed. Even once it drys on your face it will bleach things so be wary.
isa n.
55 reviews
Beauty Junkie Expert Level 1
Works great! This is my secret weapon when it comes to a big event coming up and I have a problem on my face, just plop that on your face where that nasty pimple is and soon enough it's gone!
Lorie L.
Chicago, IL
55 reviews
Beauty Junkie Expert Level 1
I use this and the stubborn acne cleanser and it helps with my cystic acne. I put it on 3 times a day and I find that it goes down but sometimes it doesn’t work as well as the other pimples
Alicia L.
Hephzibah, GA
35 reviews
Beauty Junkie Expert Level 1
One of the best acne spot treatments that you can get over the counter. Works fast and no irritation or burning after application. Dab it on the problem area at night and when you wake up the spot is gone usually and if not its noticeably smaller.
Erika S.
Menifee, CA
49 reviews
This has been one of my Holy Grail skin products for years. I have never actually had acne, but I credit this stuff for keeping my skin clear. Whenever I feel even the possible making of a pimple, I apply a dab of this on top before going to bed, and it literally zaps it away. For clear skin purposes I also use this nightly on my chin, forehead, nose, and smile lines to dry out potential pimples before they start - it never irritates my sensitive skin, and is super cost-effective. DEFINITE RE-BUY.
Juliet L.
238 reviews
Beauty Junkie Expert Level 5
I love this product!  I used to use Epiduo and that was getting really expensive. I've tried the acne free treatment but it dried out my skin so badly.  I've been using this treatment for three years now and my face has stayed relatively clear.  I use this in conjunction with my tea tree toner from the body shop and my face stays clear most of the year.  I love that this has benzoyl peroxide instead of Salicylic acid.  Plus, it's at 5% rather than 10% so it's not too harsh on my skin  And Ulta always has this as a part of their BOGO sale and you can use a coupon! SCORE!
Kylie B.
Littleton, CO
15 reviews
This is my go to spot remover!  If i have a blemish i reach for this product. I am a repeat customer. For the money and the effectiveness of this product it cannot be beat. After cleaning i put a dab of this product on the blemish. I rub it in and then i go to bed. In the morning the blemish is either on its way out or gone altogether. It is truly the best acne treatment i have ever used. It does not burn or dry out the surrounding skin at all. There is no discoloration of the skin nor does it sting going on. Great product. You can purchase this cream at your local drug store or Target or Walgreens. 
Haley K.
Orlando
61 reviews
Beauty Junkie Expert Level 2
I like to use this on pimples that have already formed or that I can spot forming under the skin. It works wonders! I use it as a spot treatment and occasionally will put it in specific areas that I know pimples form easily (like around my nose and on my chin). Sometimes after one night of having it on, the pimple is gone! The only con that I can think of is that if you apply too much it gets a little crusty in the area but that's it!
Used to use a lot as a teen, good for the price. I have since found better products for myself that are more effective. Doesn’t work on millia, blackheads, or cystic acne.
Kaleb F.
Stoughton, MA
137 reviews
Beauty Junkie Expert Level 2
I like this product and find that after a couple of days using this on acne that my blemishes are reduced in size and intensity and are on the way to healing. However, for the price I would rather use the Clean & Clear® Advantage® Acne Spot Treatment because I think it works a little faster and is a little more powerful for acne spot-treatment.

It applies smoothly, and doesn’t cause me much if any of a tingling or other sensation. There isn’t much of an odor to this either, which I quite appreciate.

This is a good product, but it isn’t the best I’ve found.
Gabrielle F.
7 reviews
Will this make my face break out if it doesn't work?
Sandra L.
West Covina, CA
36 reviews
If you weren't satisfied with this product, which ones would you recommend?
I have very sensitive skin. Most acne treatments are too harsh on my skin. Do you think this would work for me?
Amelia L.
Oregon, WI
9 reviews
Does this actually work? Is it worth the cheaper price?
Layla G.
6 reviews
I don't have acne, just one or so breakouts, would you recommend this as a quick, fast, and simple product for that? I know it does depends on skin type.

Sign up to join our community!

BackInfluenster Cashback
Neutrogena® On-the-Spot® Acne Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.