Dietary Supplement. Brighten Your Day! With St. John s Wort & 5-HTP If you feel like a dark cloud has been following you, try the HTP.Calm™ supplement. Its unique combination of 5-HTP and St. John s Wort with other natural ingredients is intended to provide nutritive support for optimism and a renewed sense of well-being. Certain feel-good neurotransmitters in the brain are important to maintaining a sunny disposition. Adequate levels of serotonin, dopamin, melatonin and others help support emotional balance and healthy nervous system function. This advanced formula combines the leading nutraceuticals known to help provide nutritive support for positive brain chemistry and a brighter mood. To help restore a positive outlook be sure to exercise regularly, follow a healthy diet and get en.