I had really high hopes for this product. It seemed to work upon the first few applications (first 1-2 days). They come in little sticker like circles that you peel off and you "apply" it to your problem area. I feel like these worked ok for smaller white head-like pimples (<1mm), BUT when I used it on a bigger pimple (2mm) a bigger and more painful pimple began to erupt. The same issue happened to my mother. Her single pimple (2mm in diameter) grew into a huge 4mm painful sized pimple. I felt terrible to have even given her these patches. I saw great reviews for this product of the website, however. I do not want to take the risk of a growing another large and painful pimple. I have combo skin, sometimes oily. I feel like the sticker cuts of the O2 needed for skin renewal, I'm sure that there are many types of bacteria within our skin that continues to thrive without the O2, so these patches probably created a perfect environment for bacteria to thrive in.