I haven't purchased the booster box of this set, but I am planning on it because the booster packs I have purchased have been really amazing. This set has a new mechanic called transform. Though this mechanic has been used before, it now applies to a wider range of werewolf creature cards, too. There are are several planeswalkers in this set that this rule applies to.
(Not only that, but there are several planeswalkers in this set, which I am super psyched about.)
This should put a good spin on gameplay. I am really excited to get more of these cards!
I will say though, if you plan on purchasing from this set, definitely get a booster box if you can. You have a better chance of getting the rarer cards. :)