These probiotics are tolerable for someone whom has SIBO. With so many probiotics on the market, it’s hard to know which ones to buy. Some can cause extreme bloating and gas; symptoms that one wants to avoid when trying to address gut health. The strains in lactoprime do not cause ill effects other strains have had on my stomach. Very good for repopulating gut health with beneficial species, especially after a round of antibiotics. I take 1 daily for maintenance. This blend needs to be refrigerated. If you order directly from Klaire Labs they ship with an ice pack to ensure quality is not compromised. This is pricey at almost 50$ a bottle but, you get what you pay for. I highly recommend this probiotic, especially if you are already dealing with gut issues like gas and bloating.