Pressure Optimizer® contains AmealPeptide®, a patented extract clinically-tested for blood pressure support. MegaNatural®-BP Grape Seed Extract is patented and clinically-tested for the support of healthy arterial function. Glycostat® Wild Bitter Melon Extract (Momordica charantia) may influence the body's nitric oxide and angiotensin converting enzyme (ACE) systems. Sesaplex™ Sesame Seed Extract lignans support antioxidant mechanisms, including the recycling of gamma-tocopherol and gamma-tocotrienol. Celery Seed traditionally is used to support kidney function. Magnesium helps to relax the blood vessels.