Helping My Mother-in-Law’s Knee Pain My mother-in-law has been suffering from bad knee pain for a while, and this Jamieson Glucosamine Chondroitin MSM has made a noticeable difference. She says her joints feel less stiff, and walking has become easier. It’s a strong formula (1300 mg) and gentle on her stomach. Great for anyone dealing with joint pain or cartilage wear.