The main difference is really the price. The Garnier moisturizing gels cost under seven dollars, whereas the Clinique Surge moisturizer is nearly forty dollars. That's a huge difference for comparable products. They both moisturize really well and are great for acne-prone skin. They both absorb really quickly into the skin and keep your face moisturized for long periods of time. If you use too much of either of them, your skin can feel slightly tacky (which isn't always a bad thing if you're going to be wearing makeup). The Garnier gel has a bit of a scent, but in my opinion, it's light and pleasant. Overall, I would say it just depends how much money you're willing to spend in order to have a high-end brand. They're both great moisturizers with very similar results.