Why use a POA (Pentacyclic Alkaloid) cat's claw extract It supports critical immune-system activity-POA cat's claw has been shown to support powerful components of a healthy immune system, including important T-cells. Why take Saventaro It's a unique - and better - extract of cat's claw-Saventaro is a standardized extract free of harmful levels of certain substances, called tetracyclic oxindole alkaloids (or TOAs ), commonly found in traditional cat's claw extracts. It is a sustainably-harvested form of cat's claw-The powerful plants used in Saventaro come to us through the generosity of the Ashaninka people of Peru. In return, a percentage of the proceeds goes toward financial support for education, medical care and the vital protection of their rainforest lands. Saventaro is clinically studied to support healthy B- and T- cell development Saventaro is the only patented, clinically studied, and guaranteed cat's claw extract to benefit both the natural and acquired immune systems. Saventaro supports healthy range of motion, too Saventaro provides beneficial POAs, compounds that support the body's natural anti-inflammatory response. By modifying the immune system, Saventaro can help support a healthy range of motion. Saventaro is a registered trademark of IMMODAL Pharmaka GmbH (Austria) and is made in the USA under license from IMMODAL.