Why is pantethine important Pantethine helps break down fat and cholesterol: Pantethine is the bioligically active form of pantothenic acid (Vitamin B5). Clinical studies demonstrate pantethine, but not pantothenic acid, can help some individuals break down fatty acids and cholesterol more effectively. Why take Cholestoril®?It helps maintain healthy cholesterol levels already within the normal range: Pantethine, like that found in Cholestoril, is essential for the breakdown of fat into energy. Clinical studies have shown that supplemental pantethine can help some individuals break down triglycerides and cholesterol more efficiently. Cholestoril is an easy addition to a heart-friendly regimen.