One of the biggest differences is the expiration date. ELF recommends that you use the mineral primer for no more than 6 months where the Essentials primer is recommended for no more than 12 months. If you look at the bottom of each primer there is a 6 M (mineral) and a 12M (essential), that's the time recommended to use product. Another difference is that the essentials primer seems to be more drying than the mineral. The mineral primer brings more moisture to your eyelids. I find that they both last a really long time.