Science-Based Nutrition™ Dietary Supplement with 400mg Active S-Adenosyl Methionine per Tablet. Enhances Mood & Neural Function. Promotes Joint Comfort & Mobility. Supports Liver Health & Detoxification. Pharmaceutical Grade 60 Enteric Coated Tablets Sealed in Blister Packs for Freshness & Convenience Our Double-Strength SAMe 400 contains 400mg of active SAMe in each tablet. Doctor s Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none. Do.