Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,755 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,794)
Q&A (507)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Min R.
Mechanicsburg, PA
1 review
Thai product really work. I got a pimple and I put this on and the next couples of day it disapear day.
Jade Y.
35 reviews
Beauty Junkie Expert Level 1
Purchased at: Amazon
Best stuff! My brothers and I fight over tubes of this stuff because we all love it. Goes on clear so it can be worn in public and actually makes pimples disappear in days
Hanna L.
37 reviews
Beauty Junkie Expert Level 1
Purchased at: Walgreens
This spot treatment kind of burnt my skin a little bit because I have very sensitive skin. But I don't have acne right now so maybe it worked. It was a little strong a kind of burnt my eyes but overall it was a nice product.
Ruby Y.
61 reviews
Beauty Junkie Expert Level 1
Super easy to use. Thia is the best way ti dry all those annoying pop up in your face. I use it only by nigth and in the morning is all dry
Cindy K.
183 reviews
Beauty Junkie Expert Level 3
This stuff does the job! Make sure to not pop the pimple beforehand , or else it will take a lot longer to heal. This does the job and only takes me a couple uses to make the problem spot go away! It is a bit drying, however.
Emily L.
Salem , OR
99 reviews
Beauty Junkie Expert Level 4
This really helped clear my pimples, I did find it drying but that is expected. I could only use a little bit because I have sensitive skin but overall really great. 
Emily L.
Frederick, MD
24 reviews
Beauty Junkie Expert Level 2
Absolutely love this stuff. One tube will last me YEARS. Dries out any pesky acne in just a couple uses. I have tried other things but I keep coming back to this one.
Jessyca M.
Portland, OR
82 reviews
Beauty Junkie Expert Level 1
I love it, it’s a quick solution for acne, I always buy it, it’s a must have... it’s really good value, you can find it at target or walmart.
Amy A.
Billerica, MA
24 reviews
Beauty Junkie Expert Level 1
Purchased at: CVS
I’m not really sure how effective it is. I’ll usually use it if I feel a pimple coming on to help prevent it from becoming bad, but it is kind of drying so I try not to overuse it.
Sarah F.
67 reviews
Beauty Junkie Expert Level 1
Purchased at: Walmart
I've never been impressed with anything from Clean & Clear. It works for a little bit and then stops working.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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