Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,717 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,722)
Q&A (493)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Drysdelle P.
Las Vegas , NV
24 reviews
Beauty Junkie Expert Level 4
Affortable and fast working product. Once I feel or see a bump coming along I do not wait and place the treatment on the spot immediately. Helping reduce the pimple before it comes
Sarah C.
43 reviews
This works okay. I really like that I can put it on at night and the next day, my pimple is smaller but I do not like that I am unable to wear this under make up. On my skin, it looks like dry flakey skin underneath foundation. The product also does not smell the best. It smells a lot like medicine. I would buy again, but only to wear at night.
Audrey G.
Winnipeg, MB
15 reviews
I have acne prone skin, and my kind of acne is cystic acne and this doesn't really help, or dry out my spots. sometimes it makes it worse and it's alcohol content is really high.
Debbie B.
Greenock, Renfrewshire
50 reviews
Beauty Junkie Expert Level 1
Omg buy this !!! This has always been my go to product when I need to get rid of pimples fast. It works so quick in the skin and you can feel it stinging but it's worth it. Definetly purchase this and I have used it and repurchased again and again
jillian💋 ..
Tullichewan , Alexandria
61 reviews
Beauty Junkie Expert Level 1
I feel this product works wonders, I always keep this in my bag as it seems to work very fast! It's gentle on the skin & felt it was effective. it's also a great price and would highly recommend , I will be buying again when this one has ran out.
Ana J.
42 reviews
Beauty Junkie Expert Level 1
This product was my HERO in my teens years!!! I bought this montly! They change the presentation tho.. But this is awesome! All my acne and blemish sking got better by the time and I dont have any problem with bad sking actually! 100% reccomended!
Natalia A.
44 reviews
Beauty Junkie Expert Level 1
Every teenager or acne sufferer must definitely buy this product! It brightens your toughest scars and removes then in just one day. It has a good price. You apply one tiny drop on the affected area at night and by morning the blemishes are gone.
Paula A.
9 reviews
es una lata igual porque dn mi país (chile) no llegan estos productos y siempre es bacán probarcosas nuevas y choras, pero acá llega muy poco producto americano, y más si uno es de región, dónde no se encuentra nada de lo que uno esta buscando. 😭
Z♕ K.
5 reviews
Really like this product as if clears my spots overnight, it met my expectations for the product and I will buy it again. I am a repeat user of thus product. Australian bought in store, would recommend to other consumers as if really works well
Sarah P.
Port Hope
36 reviews
I think that the price for this product was ok. It came in a small container. I had purchased it at shoppers. It didn't really meet my expectations. I think that the price is a little pricey for the size container. It should be a little cheaper or make a bigger container for it.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

Influenster Cashback
We recorded your visit.
Clean & Clear® Advantage® Acne Spot Treatment

Amazon was opened in another window. If you made a purchase Cash Back will be automatically added to your Ebates account tomorrow.

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.