Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,294 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10294)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Arianna C.
Miami, FL
50 reviews
Beauty Junkie Expert Level 2
This product is so great! I'm a teenager that has been struggling with acne for a few years and this product has changed my skin within a week! Areas where I have had acne for a few years have become smooth and are already clearing up! This product is also great at preventing acne! I put it whenever I feel a bump coming and it works it's magic! This product is such a lifesaver!
laura t.
north bay ontario
8 reviews
I believe in speaking the truth and being honest and I find this product did not work for me at all it's not as great as everyone says it is and I think it made my face break out more J's
Abby C.
Glasgow, Glasgow
5 reviews
Beauty Junkie Expert Level 1
I use this on acne spots that pop up from time to time. It normally works pretty well at getting them under control quickly, but maybe once in every 5 spots it does absolutely nothing.
Ashley M.
Middle Sackville, NS
11 reviews
Clean & Clear is the best name this company could have. It's accurate. This product works miracles on my sensitive skin. Whenever I get a breakout, I reach for this. Works fast and well!
Carla C.
Fajardo, PR
7 reviews
OMG is the best word that describe this product. It defenetly work, is like magic. I put the product in my face and the next day the pimples has disappeared and reduce swelling
Rebecca M.
12 reviews
Beauty Junkie Expert Level 1
It felt great on my face and it did make a little difference on my acne although I wouldn't expect very fast results with the product. In time though it does make a difference.
chaimaa E.
El jadida
86 reviews
Beauty Junkie Expert Level 2
i have heard best reviews about this product and i'm very excited to try it! i would like to try it  from you for free Vox Box testing and sharing my view and product with my followers on my public insta page  Clean & Clear® Advantage® Acne Spot Treatment
Momoo L.
43 reviews
It's a nice product for big pimples and removes them within 2 days or sometime in 1 day.
but the thing is i didn't even pooked the pimple still their are some scars from it
Naveen  D.
6 reviews
I have very very sensitive skin but luckily this product didn't cause a skin reaction. However, this product was drying out my skin yet didn't do much for the blemishes.
Emily H.
32 reviews
Beauty Junkie Expert Level 1
Great product! I came across this a few days ago at the drug store and it works wonders!! I use it almost daily and I would honestly recommend this over any other product I've tried. Best out there in my opinion!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

BackInfluenster Cashback
Clean & Clear® Advantage® Acne Spot Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.