Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,523 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10523)
Q&A (464)
Media (121)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
stacey b.
Sheffield, ['', '', 'Sheffield South Yorkshire ']
37 reviews
Beauty Junkie Expert Level 1
Within a couple of days this treatment had my skin back to perfection. It's the best acne treatment around in my opinion and is pretty much the only product I reach for when I have breakouts. Unfortunately you can't apply makeup over the top of the treatment as it peels off but without makeup it forms a layer over your spots to get rid of them as quickly as possible
Yaya S.
Haifa, IL
287 reviews
Beauty Junkie Expert Level 4
Super nice, makes it job perfectly.
Good price and Worth's it indeed.
Highly recommenced, go try yours and let us know what you think.
I love it, love the feeling of it on my skin and easy to apply afterall. 
this brand is known for its super high quality products and fine prices, once you try this you will never go back
Basma A.
29 reviews
I suffered with some acne spots in the last couple of months, but after I used thi,s it had improved my acne so much most of it is not even there. Great product highly recommended.
Jealyn joy e.
5 reviews
This is my hero! Nothing can treat better my acne spot than clean and clear. I have tried different brands but this one really works for me. Compare to any other acne treatment product, it has a very good value, not so pricey. I never run out of stock because this is one of my 'must have' items in my bag.
كرستينا ا.
Waterlooville, London
32 reviews
Beauty Junkie Expert Level 1
Recently I've been breaking out during summer time and I needed something desperately to treat the area quickly, this product helped me very much, I got rid of pimples, BUT where I applied the product ( only on the spots, ofc) my skin dried out and when I apply foundation over it looks cakey! Still a great product and using it every time to zap those mofos 🙈
Anna T.
4 reviews
I used this product for about a whole month and it took away all my pimples. It meets my expectations because it drys in a day. The product is very gentle though it burns a little bit in the beginning but is not so painful later. I recommend this product for those who have acne spots
Mikayla C.
Toronto , ON
336 reviews
Beauty Junkie Expert Level 5
This product was good for the occasional spot treatment but if you have recurring acne its not the best long term solution. It does help reduce size and redness but I wouldn't say its better or faster than other brands in the market. If you're looking for something new though you will see results with this!
Liberty S.
46 reviews
Beauty Junkie Expert Level 1
Honestly, I didn't love this. It dried my skin out, not the kind that helps get over spots, the kind that makes your face tight and itchy, makes you feel that your coming out in a rash. Obviously I never put it all around my face but when I had acne problems it was spread in a wide area. I do not recommend however do tell people to give it a try if they are interested as it is a cheeper product and it could just be my skin that react with it!
Sarah-Nicole M.
13 reviews
I don't typically struggle with much acne at all, however around that time of the month I tend to get a pimple or two. I used to just leave them and let them heal on their own which was bothersome. One of my friends recommended this to me, and I'm so glad she did! It will dry up your pimple overnight easily. And although it might leave somewhat of a dry patch, all it takes is a little bit of moisturizing to fix that! If you want fast results for little money, this is your best bet!
BiJun X.
12 reviews
This was the best drugstore product i've bought for my pimples. I've used this brand for my pimples since middle school and it still works amazing. My pimples disappear overnight! If i use it in the morning, it'll clear up by the next day but gradually becomes smaller throughout the day. However, i don't have major acne problems so this is great if you just have a random pimple that appears.   
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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