Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,545 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10545)
Q&A (464)
Media (121)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Seren Haf G.
15 reviews
This helps my skin so much I put it on before I go to bed and wake up feeling fresh , the answers start showing after a couple weeks so don’t get your hopes up if your spots ain’t there by the next morning
Lauren L.
Port Moody, BC
223 reviews
Beauty Junkie Expert Level 5
Good product. Cheap and effective. Best not to use too many days in a row as it can make skin quite flaky. Good value and can be purchased at almost every grocery store or drugstore.
Rebeca D.
San Ysidro, CA
649 reviews
Beauty Junkie Expert Level 5
I often apply this product, sometimes it work, sometimes it does not, maybe it depends on the imperfection. It is really gentle with your skin and in small pimps it is effective.
Katelynn 🎀.
38 reviews
Don't use it as much anymore but back in highschool this really helped my acne out a lot. Use to work overnight and I didn't have to worry about pictures of anything. It was nice
Leanne :.
Riverview, NB
61 reviews
Beauty Junkie Expert Level 2
I love it!!!!!!!!!!!!!!!!!!!!!! It kind of dries my skin up a bit every now and then, but its worth it because when i put it on a zit the night before, its gone by the morning!!!!!!! Would definitely recommend and buy again!
Gessica L.
Miami, FL
68 reviews
Beauty Junkie Expert Level 1
es lo maximo!!!!! la uso como primer cada mañana, te ayuda a mitificar y a reducir los poros sin resecar demasido la piel, ademas que se consigue en cualquier supermercado.
Michelle B.
13 reviews
Beauty Junkie Expert Level 1
This is amazing for any break outs you are having , it cleans out any bacteria within the break out and removes the break out within a day or two. Highly recomend for breakouts
Shaghayegh N.
3 reviews
This product does what it claims. I'm not sure if it's just my skin that rests to it really fast but it really does remove
Dark spots that are left after I scratch pimples off.
Rea Erika G.
9 reviews
Beauty Junkie Expert Level 1
Great for cystic acne, and you know it works because there is a light sting. When you place this product overnight, you can see a major difference in size by the next morning.
Jodie T.
Oakville , ON
38 reviews
Beauty Junkie Expert Level 1
Really helps clear my acne when I leave it on overnight. Could be alittle frustrating sometimes when you forget you had it on and accidently rub it off. The smell is quite strong so keep that in mind.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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