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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,293 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10293)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Brianna F.
Ottawa, ON
23 reviews
Beauty Junkie Expert Level 1
I love this spot treatment! It’s an over night wonder that works while your sleeping. I wouldn’t use this under makeup though, as it does have a thick gel texture
María  De Jesús R.
9 reviews
Beauty Junkie Expert Level 1
I LOVE THIS PRODUCT. I'm a little bit of acne, and it helped me a lot. The products I used did not lend me so much, I tried this and it was really great. My complexion was cleansed a lot. I really love him madly.
Maria L.
Goleta, CA
22 reviews
I have been using this since my first outbreak ever back in junior high. It works amazingly even until today when I am 7 years older than back then. It doesn't dry your skin out like other products. I have tried Murad spot corrector and Clinique which are way more expensive and they still don't do what this has done for me. Around 3 days later, pimples will disappear completely. I mainly get them on the side of my cheeks. It feels cooling and does reduce redness. I really recommend especially if you're on a budget.
isabella r.
125 reviews
I really liked this product and would definitely purchase this again. The quality was great and the product did just what it was advertised for. I like this item a lot and it was a perfect fit for me! I does have some parts that could improve.
sally p.
8 reviews
It definitely reduces the appearance of spots however it does not get rid of them like i wanted it to. it is an invisible gel which is good because you can't tell it's on your face.
Vanessa F.
3 reviews
This is a very good product and I really saw a reduction in my spot within 4 hours of application. However I would a recommend that this product was used before applying make up (although the product states you can use it either way) but I found that the product tends to flake on the skin after it goes dry, however this flakiness is unnoticeable under makeup. 
Overall I would recommend this product, it comes in a nice, small and simple package and can easily fit in you bag with the rest of your day to day essentials.
Kimberly S.
81 reviews
Beauty Junkie Expert Level 3
Use this when I get a bad breakout and their gone usually by the next day I have used it alone and under my makeup and I find it still works just as good been using it for years now
Janaína F.
1490 reviews
Your week is about to be filled with shopping? If you're looking for find a store for a small therapy purchase (you don't need an excuse not to go). We seek by some shopping that are worth it. Go ahead, treat yourself, enjoy. And good purchases!!!
Camila M.
2 reviews
It's a good product, but in my personal experience it only works on spots that appear during the period but is not the same story with acne spots, because it tend to overdry the skin,
Meaghan H.
1 review
I used to use this product when I was in middle school/high school. It worked for me though u had a bad picking problem so it didn't work as well as it probably could have. I also used this before I knew much about skin care and I didn't realize how much this was drying out my skin. Overall, this product can be helpful for whiteheads but it wasn't the best spot treatment I've ever used (sorry this review is all over the place)
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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