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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,330 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10330)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
abhiri n.
14 reviews
Beauty Junkie Expert Level 1
Uses this honestly not too long but doesn't really work. Has a typical drugstore fragrance in a good way. Does have salicylic adidas an active ingredient so could help milder forms of acne
Mandi D.
Mississauga, WY
74 reviews
Beauty Junkie Expert Level 3
This is a great drug store spot treatment vut it is super dying . I have naturally dry skin so if i use this frequently my skin cracks and gets really dry . So its great for the occasional breakout but if you have dry skin like Me i wouldn't recommend this for regular use .
Jessica R.
53 reviews
Beauty Junkie Expert Level 1
Put a dot of product on your pimple, don't mess with it, and let the gel act to dry it, shrink it down, and make it disappear! I've been using this stuff for years and I have never been disappointed. Will be getting it forever (or for as long as I get pimples).
Valentina C.
15 reviews
Beauty Junkie Expert Level 1
I swear by this product, it's by far one of my favorites!! You only have to use a small bit and you put it on a pimple at night and by the next morning it will have dried it out. Then you wait a couple days and it will disappear. It stings a little bit but beauty is pain, it's very worth it! It's also not too expensive considering that you don't use much of it!
Savannah S.
Ballymena, Antrim
17 reviews
Beauty Junkie Expert Level 1
Been struggling with bad skin and scarring from mild acne for a long time. This was so gentle on the skin. I bought this from my local pharmacy. I've bought this twice since I first bought it as I love it that much and I would definitely recommend this product.
Charlie W.
28 reviews
This product is fab. Clears any of my red blemishes within an hour or two!!! And when paired up with the scrub and toner it does wonders. It is harsh so wouldn't recommend for people with sensitive skin. If you have normal skin I would say definitely give it a go
Liberth D.
Miami, FL
133 reviews
Beauty Junkie Expert Level 3
This producton is excellent when we have some outbreak of acne because it stops the growth of the nugget and dries them almost immediately disappearing redness and granite as such! I recommend it extensively and much more in cases of emergency when we leave those undesired items
Catarina C.
14 reviews
Great product with great results for a great price. I love the packaging and I will for sure buy this again even though i have only used it once. It's one of the most effective products I've tried in a while. I will most definitely recommend this to my friends.
Margaret P.
3 reviews
I've had a couple of tubes of this product and I have mixed thoughts about how it performs. I actually liked it at first as it helps to make my pimples dry faster and heal faster but it does not help my pimples marks to disappear faster than i want it to. 
Leela N.
Leicester , Uk
14 reviews
This is a good product for spots.
It helped keep them down and the next day they wouldn't be as bad.. but the only thing is if you have skin that's easily upset by new things in your skin care then it can feel itchy and can feel like it's burning a little .
But it does what it's meant to do by reducing spots .
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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