Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,451)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Alexandria M.
Troy, OH
57 reviews
Beauty Junkie Expert Level 1
I've been using this acne product for a while now just in case I get a pop up blemish/pimpl. It works really well, and greatly reduced the acne spot within a day!
Ashley B.
Bel Air, MD
15 reviews
Beauty Junkie Expert Level 1
Purchased at: CVS
I put this on as soon as i see any sort of blemish on my face and with in 2 days at max, its completely gone. I definitely recommend it and it is a really good price, especially for how long it lasts.Clean & Clear® Advantage® Acne Spot Treatment
Mariah M.
La Plata
94 reviews
Beauty Junkie Expert Level 3
Purchased at: Amazon
It works ok, it just leaves your face feeling very drying and kind of itchy. It does work but if you have sensitive skin I wouldn't recommend using too much of it.
Chloe G.
Paso Robles , CA
45 reviews
Beauty Junkie Expert Level 1
Purchased at: Rite Aid
This is a great product for spot treatment on unwanted acne appearances. Just a dab on the zit and it’ll be gone the next day. Great product!
Savannah R.
Gretna, LA
57 reviews
Beauty Junkie Expert Level 1
Purchased at: Target
This product works great on wet recently washed skin. It doesn’t work immediately but after a few days the blemish seems to disappear. I’ve never gotten any dry spots or marks from this product so that’s a plus. I would repurchase .
Jackie d.
4 reviews
Beauty Junkie Expert Level 1
Purchased at: Walgreens
This is my favorite acne spot treatment it has cleared my skin and i am looking forward to buying another one. This is so effective for my skin and it’s at its best right now. I would recommend it to others to try
McKenzie F.
8 reviews
I have used this product for the last 6 years and it continues to impress me. It’s apart of my two-a-day face routine and instantly minimizes pores and pimples.
Ashley M.
Boynton Beach
225 reviews
Beauty Junkie Expert Level 1
This product works so quickly. It amazing how effective this is. Any time I have a break out, I will put this treatment directly on once or twice that day and it will be almost or entirely gone by the evening. I have got a few others hooked on this. I would highly recommend. 
Hayley B.
Jonesboro, AR
17 reviews
Purchased at: Walmart
I love this product! I feel like I would use this as soon as a pimple would appear and the next morning it would be gone!
Eriu A.
8 reviews
Purchased at: Amazon
This product is one of my absolute favorite! It works great and cleared up my face super quick,! Definitely will buy again
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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