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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,328 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10328)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Jessica M.
81 reviews
Beauty Junkie Expert Level 2
Works amazing on large pimples that you want to shrink over time. I learned the hard way to not use too much - I applied a huge glob all over my chin and it ate away at my skin. Don’t worry it’s fine now :). Use in moderation.
Jessica W.
Halifax, NS
69 reviews
Beauty Junkie Expert Level 1
Hands down the best! It works super well, my spots disappear overnight. I’m on my fifth tube! Not to mention, it’s super affordable and when used cautiously it isn’t too rough on my skin. I will be buying this forever and ever.
Najjo I.
Preston, Lancashire
50 reviews
Beauty Junkie Expert Level 1
It worked brilliantly for me I would apply this as soon as the spot made appearance and I would notice it helped to reduce the redness and t wouldn’t be that itchy.
I would recommend this product to others as it helps a lot
Danielle B.
Truro, NS
21 reviews
Beauty Junkie Expert Level 1
purchase this at my local Walmart, was very impressed with the outcome of this product. It has a strong scent but it’s bearable to deal with. A little goes a long way and it is inexpensive while it still works very well and you will see a difference once using it.
jessica k.
106 reviews
Beauty Junkie Expert Level 2
I love everything else from clean and clear.. apart from this. To put it bluntly it just does not work for people with spot prone skin. I was extremely disappointed when I tried it out. Might try it again but for now it’s a no no.
Ellie C.
5 reviews
Beauty Junkie Expert Level 1
This honestly did not do much for me. I do not like the smell. It has great packaging though, very easy to put on the skin. I have used it many times but it doesn't do much, and I find it harsh on my sensitive skin. I prefer other clean and clear spot treatments
María Alejandra O.
Doral, FL
18 reviews
Beauty Junkie Expert Level 3
Este producto es genial. Cumple su objetivo que es librarnos del acné. En toda mi adolescencia el acné a estado presente, y eso es algo muy incomodo de tener, sobre todo en esta etapa de nuestras vidas, y definitivamente este tratamiento funciona genial para quitar esas imperfecciones que brotan en nuestro rostro.
Rojin💕 T.
89 reviews
Beauty Junkie Expert Level 2
I brought this for real cheap at my local Superdrug store and wasn’t expecting much for its price however it worked like magic for my skin. I apply it on my spots and help a lot. I would definitely recommend it to others.
Poonam K.
42 reviews
Beauty Junkie Expert Level 1
It is a good cleanser, washes off the dirts, keeps away pimples or acne, and also the whiteheads which occur due to the accumulation of oil in the pores Clean & Clear® Advantage® Acne Control 3-in-1 Foaming Face Wash
Stephanie C.
15 reviews
Beauty Junkie Expert Level 1
Life Saver. That's really all I can say with the Clean and Clear Advanting Acne Spot Treatment. Small and compact making it easy to take on-the-go. I found it to be very effective leading to more purchases. Would definitely recommend to others looking for fast results before a nigh out or special occasion.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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