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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,294 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10294)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Poppy A.
43 reviews
Beauty Junkie Expert Level 1
The packaging of is basic and I felt you did not get much product,
(although it was fairly cheap). It cleared my spots up literally over night or reduced them significantly in size. My skin did actually sting on certain places where I had applied the product however for me this was not something that bothered me as the results I got were really good. This is not a treatment for acne despite claimed as it treated reoccurring spots on the surface and not the underlying source of the problem which was treated through a dermatologist.
Sheena L.
106 reviews
Beauty Junkie Expert Level 4
I am a huge fan of this product. Within two days of applying this product i notice a reduce in redness and size of my blemishes. This product is very affordable and can be purchased at target or walmart. This product is very gentle and doesnt irritate my sensitive skin. I recommend this product to people who suffer from occasional blemishes
Fiona M.
44 reviews
Beauty Junkie Expert Level 1
This stuff is magic. Pop a little bit on a spot or blemish that has either appeared on the surface of the skin or is trying to appear, leave it to sink in and the next day the spot/blemish is gone. The only criticism is that it is quite drying, at least it is for me but I already have dry skin. I find that using a decent moisturiser combats this nicely so I don't mind the dryness.
Caitlin d.
16 reviews
Beauty Junkie Expert Level 1
I purchased this after running out of the Mario Badescu Drying Lotion, as i was looking for a more easily accessible and cheaper alternative, that delivered equally as impressive results. This product is different to a drying lotion as it is a gel, however because of this it makes it far more versatile! I used it overnight and occasionally during the day underneath makeup as well!
Sophie D.
6 reviews
This is a great spot treatment to help reduce breakouts. I found it to be a very good and easy product to use. I wouldn't say it reduced the spot within a few hours I would use this product 2-3 days before to make the breakout smaller before a big event. It is easily accessible and affordable to
yyyy x.
145 reviews
Beauty Junkie Expert Level 3
I didn't like this. Yes, it's cheaper than a lot of other brands. But, it's also not nearly as good. It did nothing for my acne, only made my face break out more. I much prefer the philosophy salicylic acid pads, they work a lot better and actually get rid of my pimples.
Elaine S.
Miami, FL
70 reviews
Beauty Junkie Expert Level 1
No se si será porque mi acné es de tipo hormonal, muy quístico, pero no me funcionó en lo absoluto. Utilizé 2 tubos durante un largo período de tiempo, de hecho lo combiné con una hidratante que conseguí de esta misma línea para potenciar su efecto, no me funcionó.
Taleah H.
9 reviews
I personally didn't see any change on my skin type and I have combination skin. Nothing really much to say the packaging is nice though very plain and simple. It's an affordable product, usually 6-8 dollars. I tried it and kinda gave up on it though seemed a little gimmicky maybe if you keep using it , it could do something but i didn't see any reason to continue using it. 
Natasha M.
13 reviews
I used this thinking it wouldn't really work! Boy was I wrong. I could totally see a difference by morning. Wherever I applied the treatment my acne was gone or a Lot smaller. My daughter recommended this to me and I've even made my husband use it when he has a stubborn breakout. Not something I need daily but when a big zit shows up this is the product you need to attack it!
Kayla L.
70 reviews
Beauty Junkie Expert Level 1
Not quite sure how effective it is, i usually put it on at night and it takes a few days to clear up but that could just be my acne naturally clearing up. Much better to use this as night because it leaves shiny spots where you applied it!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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