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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,280 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10280)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Fernando Rances Y.
Doral, FL
484 reviews
Beauty Junkie Expert Level 4
Cuando estaba buscando un producto para ayudar a mis cicatrices de acné y granos porque me gustaría recoger en ellos me estaba buscando loco por un producto que funcionaría porque estaba teniendo eventos especiales que viene en mi cara era sólo malo y necesitaba algo Para tratarlo realmente rápido. Cuando estaba mirando hacia fuera en línea vi este proyecto y yo era como necesito comprarlo rápidamente porque mi cara estaba apenas consiguiendo peor mientras que los días se acercaron cuando primero lo conseguí pensé que era muy barato y cuando lo puse por primera vez Era muy refrescante y hormigueo y funcionando así que seguí usando y usando en mi cara se puso mejor y mejor es uno de mis productos favoritos, aunque mi cara es muy sensible y ni siquiera tengo una irritación en mi La cara consigue realmente irritado realmente rápidamente incluso con el champú o el lavado del cuerpo así que 'Sí, recomendaría este producto
Alayna L.
Sudbury ontario
26 reviews
Beauty Junkie Expert Level 1
I don't like this product very much I've used it a lot and been looking for a better one that's cheap as well it just doesn't seem to be working for my skin type.
Chloe B.
110 reviews
Beauty Junkie Expert Level 2
This Acne product I’d say is really good and works really well it’s so effective! The packaging is really cool!!!
I’m not one for acne and my skin isn’t actually bad occasional sport and pores but I like to use all sorts of creams and serums! And I felt when I applied this product made me face look so much better even though I didn’t have acne ?

Just had such a glowing skin, all my imperfections were all
Blurred out! And my skin looks amazing! Will defo be buying another!
So I would recommend buying this!
Grace M.
19 reviews
Beauty Junkie Expert Level 1
Basically just dries out any pimples you have and works within a couple days if you use once every night. The only thing is it sometimes leaves me with a small acne scar.
Winter M.
9 reviews
Beauty Junkie Expert Level 1
This works great you can feel it tingle when it is applied to problem areas and when left on over night you can see it has drawn out the spot the next morning 
Remy S.
Winnipeg, MB
35 reviews
Travelling or at home I cannot live through a pimple without this. It zaps them all - and I've even used this on body blemishes before. Works like a charm. The squeeze tube is easy to use, it's the perfect size product to even take with you in your purse (if the situation is emergency level and you have to apply on the go). You can dab a bit on and don't have to do a full treatment. I've used this overnight and it will kill any inflammation redness and buildup under the skin by morning. Reduces the huge issues to manageable, cover-up ready spots. An essential in my skincare bag and you shouldn't go another day without picking it up (super affordable, available at any drugstore).
Alex C.
Stouffville, ON
19 reviews
Beauty Junkie Expert Level 1
Clean and clear has been the ONLY drugstore skincare brand that has ever genuinely worked miracles for my face. The Clean & Clear Advantage Acne Spot Treatment has been an amazing product for clearing spots within 1-2 days MAX. The clear formula makes it wearable throughout the day out in public, but also great for putting on right before bed and not having to worry about getting product all over your sheets! Within hours the treatment takes away the redness of my spot, reduces swelling AND advances the healing process of the skin. I have never had any scars left from a spot using this product. 10/10 recommend this product and is definitely a day-to-day essential for me! 
ibtissame a.
150 reviews
It is a pass of product is one of my favorites without a doubt I would buy it again and again with my eyes closed. I would love to collaborate with this brand because it is very worthwhile. it's a product pass
Tiare B.
Vancouver , BC
27 reviews
Beauty Junkie Expert Level 1
I have been using this product since I was in high school (so nearing about 5 years). The price tag on this guy is on the more expensive side for something this small, but a little goes a long way! I use this spot treatment right after I have popped a pimple and the next day its GONE. This is such a holy grail skin care product for me because it never fails to work on my skin. The only downside is that when I wake up in the morning, the area I applied the treatment is on the drier side, so be sure to wash your face (and maybe apply moisturizer to the area) before you put on makeup for the day or your foundation/concealer may look dry and patchy. 
Natalie P.
63 reviews
Beauty Junkie Expert Level 1
This product is super good for acne. I had a lot of small pimples on my forehead that really bugged me. I put it on twice a day for like 3 months and noticed a huge difference! Although after a while of using it your skin will become prone to it and get used to the product and won’t work as much. That’s why i switch out my products every month to help clear my skin! Worked pretty well though and it isn’t expensive! I strongly suggest this product with people in the same scenario.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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