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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,292 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10292)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Clarissa C.
Dartmouth, NS
249 reviews
Beauty Junkie Expert Level 3
This particular acne spot treatment I found worked Great! Very fast and easy to use, especially on the big ones (yuk!), it is the perfect size for your overnight bag so you never have to worry about embarrassing zits. Iwouldn't change a thing about this great product!
Ashley W.
Chilliwack, BC
4 reviews
It’s ok, if you’ve been trying to pop the pimple it will sting if you put this on. But gets rid of the pimples pretty quick. I’ve used this a few times and repurchased it. You can get it at Walmart or any drugstore. I’d recommend if you don’t have sensitive skin. 
Chelsea S.
Terrace, BC
18 reviews
Beauty Junkie Expert Level 1
First off, I did like the formula of this product. Some acne spot treatments can be super drying and then my makeup looks really crusty over it. Secondly, it didn't really do much for me. I didn't notice it improving my acne much at all. So, this one is a pass for me.
Miranda P.
Port Hawkesbury, NS
39 reviews
Beauty Junkie Expert Level 1
I find this does “work” but it dries the acne out so bad that it just makes your skin flaky in that specific spot. You could never apply makeup the next day after using this, you would be better off not treating the pimple- it would bring less attention to that spot.
Noemie P.
16 reviews
Beauty Junkie Expert Level 1
This is one of my favourite products I ever use for my acne treatment! You put it on the spot you have your acne and the next day it literally does a difference! I don’t know if it work really well like that for everyone but for me it does I really love this product!
Shayla L.
Victoria , WY
105 reviews
Beauty Junkie Expert Level 2
I find that it works well at minimizing pimples, but I also find that when I use it often, when I stop using it I break out even more than before? Could be coincidence but I dunno. Seems like it's making me have to use the product, but at least the product does work
Dylan T.
48 reviews
Beauty Junkie Expert Level 1
Helps control any breakouts and incoming spots and helps to smallen them before they get too out of control. But does not help acne scars, you will need another product for that
Jana E.
19 reviews
Beauty Junkie Expert Level 1
I bought this product as a spot treatment for my acne and I can’t tell if it has done anything at all. It leaves a bit of a tingly feeling on your skin when you first put it on. Probably wouldn’t buy this again but I’ll continue to use it until the product runs out.
Natasha M.
New Westminster, AK
36 reviews
Beauty Junkie Expert Level 1
My go to stop treatment! I’ve been using it for years to get rid of breakouts and acne. Just put it on your acne before bed, sleep, and you’ll wake up with it reduced in size :) it won’t fix your acne in 24 hours, but will defiantly help to minimize the appearance!
🌟Gem🌟 D.
35 reviews
Beauty Junkie Expert Level 1
This product I think doesn’t do anything for my acne. The packaging is nice but it doesn’t “work wonders.” I have oily skin which could be a problem. I’m a repeated user thinking it will work at some point but I still get disappointed.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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