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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,292 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10292)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Tee Z.
11 reviews
This gives great results and my spots would go away or reduce within a few hours which was really good especially when I had to go to school. It’s quite cheap which is good but it also stings the skin a bit.
Trisha V.
Tanza, Cavite
18 reviews
Beauty Junkie Expert Level 1
A vlogger once mentioned about the amazing effect of this product, and it really works. It lightens the spots made by an acne and it makes the face look blooming each day. Having an oily and acne prone skin like me, this product has an amazing ingredient that helps the traces of pimples gone forever. 
Madi S.
11 reviews
My acne wasn't terrible but it it kept it at a happy medium. But if you miss even one day it tends to flare up. I thought it was cute in packaging and such but I wouldn't use it again cause it didn't solve the problem completely it only really pushed it to the side slightly wouldn't recommend if trying for blemishless skin
Emilie M.
69 reviews
Beauty Junkie Expert Level 1
This product definitely works although it is extremely drying so only use as a spot treatment. follow the directions that they advise on the back of the product. But it definitely reduces redness and takes away your pimple overnight especially large under the skin pimples.
Kim H.
Port Alberni
43 reviews
Beauty Junkie Expert Level 1
First time I got this product it was a free trial, turned out to be a game changer. Have applied to not horrible pimples and by the evening it is down to easy to cover, applied to horrific horror show ones it took a day to two days to really see improvement, which really compared to other products I have tried is amazing.
Christina A.
Scarborough , CA
117 reviews
Beauty Junkie Expert Level 2
I do really like this product but it take a couple of days for it to actually work and to dry. It also leaves the area around the pimple extremely dry so it’s very important to only put it on the pimple you are trying to treat. It’s not too expensive either that’s why I still use it.
Courteney D.
44 reviews
Beauty Junkie Expert Level 1
My favourite acne spa treatment, I've been using it for years and can't complain. Always gets the job done, I recommend it to all my friends that suffer with bad skin. Really soft formula on the skin and doesn't leave your face feeling dry like most other facial products!
Heather T.
36 reviews
Beauty Junkie Expert Level 1
Very effective but use sparingly, too much can irritate sensitive skin and I personally prefer No7 Beautiful Skin Rapid Blemish Rescue . It is a bit on the pricier side so if you’d rather a more affordable product the clean and clear is definitely for you.
Emma R.
23 reviews
This spot treatment is relatively effective. It is (predictably) a bit drying, but nothing a light moisturizer can’t fix. At a reasonable price, it is worth the money, but I’m on the lookout for something even more effective.
angy C.
Miami, FL
29 reviews
Beauty Junkie Expert Level 1
For me, acne has never been a problem. I think I've only had it sometimes. clean & clear is very effective but for my skin that does not have acne is very strong, so I only apply little amount.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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