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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,307 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10307)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kimberly J.
1 review
Don’t like this product it left white marks on my spots after I used it and I saw no differences in my skin.Personally,I won’t be purchasing it again as I was very dissaponted with the results and don’t think it was worth my money.However,it may work better on you than it didn’t on me.
Courtney B.
Montrose, BC
402 reviews
Beauty Junkie Expert Level 3
I don’t usually get acne or very many breakouts but when it’s that time of the month I just put this all over my face and usually I can avoid the whole awkward huge pimple on my face. It’s sick
Rebecca L.
16 reviews
Beauty Junkie Expert Level 2
Does the job and decreases the redness but doesn't quite work the miracles it should and is a little oily for my liking. Found the same product for much cheaper but if you're trying to stick to a brand or need something you know will do the job then definitely reach for this product.
k² K.
4 reviews
I have been using this product for only a few weeks, but with consistent application, it does its job! It certainly helps reduce the look of my pimples, but there is still a dark spot leftover. It also helps prevent me from touching my blemishes, since I do not want to wipe the treatment away ;) 
Veronica A.
Miami, FL
18 reviews
Personalmente me encanta esta marca de productos, especificamente este tratamiento me elimina rapidamente los granos que me salen, casi por arte de magia, sin embargo, suele resecarme la zona en la que la coloque. Igualmente la volveria a comprar porque es muy eficaz con los granos.
Mia S.
15 reviews
Beauty Junkie Expert Level 1
This product isn’t something I rave about especially not compared to all the other products I have by clean and clear which is my holy grail skin care brand, but this product does help with my spots on some occasions, but because of that I don’t see myself reaching for it that often.
Camila A.
13 reviews
😍 in love with this product! It’s simple to use and it helps a lot. I usually use it at night before going to be and I put it right on the spot I want to treat. I really recommended!!
Miskan A.
143 reviews
Beauty Junkie Expert Level 2
I feel like this should be in every girls skin care routine! The product is quite gentle and soft on the face and works pretty good x it's good for its price and definitely recommend it to my lovelies x
Rebecca L.
10 reviews
This clean & clear product was highly recommended to me by friends so i purchased it myself.
I had it a long time ago and i repurchased it as i remember it working great on my skin however the second time using it was not as great as i remember.
It is a great price and does help big breakouts but its claims are fairly exaggerated and it takes a few days of use to bring big breakouts down.
I would still recommend it as it is nice to put on spots overnight.
Charlie W.
25 reviews
Beauty Junkie Expert Level 1
• dries out blemishes quickly
• strong smell but it is bearable 
• easily accessible and cheap 
• very easy to use
• dries the skin out slightly but can easily be fixed
• great size for travelling
• good for when you don’t want to treat your whole face
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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