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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars47%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,264 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10264)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Jessica B.
12 reviews
Amazing product! This always works no matter the size of my spot. I clean my face and put this on before my moisturizer and the next day it’s half the size it was
Molly B.
18 reviews
Beauty Junkie Expert Level 1
I can put this on a baby just-starting-to-look-like-a-bump pimple at night and by morning it’s dried up! Also I like putting this on ingrown hairs because it dries them up and keeps them from turning into infection.
12 reviews
Beauty Junkie Expert Level 1
I actually really like this product because it works I would say this product only works if you have little pimples and not big ones and this doesn’t work for acne scars only smaller pimples. It depends on your skin condition so this might work for you.
Sophie A.
Roswell, GA
36 reviews
Beauty Junkie Expert Level 1
It’s just okay in my opinion. There are better spot treatments around the same price range than this one. I don’t think it works super well or shows any huge differences the next day. Probably wouldn’t buy it again.
Janna C.
11 reviews
Not my favorite. It didn’t really work how i wanted it to, and it burned and severely dried out the area. The price was fine but not worth it. I don’t think i would recommend this to anyone. And i won’t buy again.
Adrian G.
Pickens, SC
52 reviews
Beauty Junkie Expert Level 1
I can’t stress enough how amazing this stuff is. It’s an absolute miracle! It treats your acne super quick, and it’s gone by the next day if you use it at night. I absolutely swear by this product. I love using it.
Tabi J.
Groveport, OH
9 reviews
Beauty Junkie Expert Level 3
This product works really well for drying out the troubled spot, but it does leave a residue if left on overnight. If you’re okay with cleaning it off with water in the morning, I recommend this for spot treatment.
Maria C.
Tuscumbia, AL
165 reviews
Beauty Junkie Expert Level 2
I love this! It goes on easily and doesn’t cause any itching or burning. It’s priced decently, too. I use this after washing my face with a face wash for oily skin and the combination helps stop/prevent break outs.
Ellen S.
85 reviews
Beauty Junkie Expert Level 2
I have been using this for years now. I have repurchased tube after tube since high school. It's my go to spot treatment. I usually only have one or two breakouts at a time and this dries them out in a couple days.
Angela G.
137 reviews
Beauty Junkie Expert Level 2
I always had little spots from where my acne was but after using this I swear that the little spots almost all disappeared the price is great and I would definitely go by this again with you and I do recommend this
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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