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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,332 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10332)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
shaima 🌸.
46 reviews
Beauty Junkie Expert Level 1
i'm beauty blogger ; my name is beautys_shaima
This is my favourite hair styler for smaller tight curls, I feel like you could create waves or loose curls with this wand but I struggle to do this. I love the style of the wand and feel it’s easy to use, the wand comes with a heat protection glove to avoid burns when wrapping you’re hair around the wand. I feel you don’t have to hold you’re hair in the wand for long at all so there’s less damage to you’re hair. The curls stay in for hours even over night in my hair.
Vanessa c.
152 reviews
Beauty Junkie Expert Level 2
Best . Sh$t. Ever !!!! 💕

If you suffer from acne or have that occasional monthly breakout ...this is your new best friend .

This little guy also helps with irritation from facial waxing , so if you’ve had brow waxing or your upper lip done, then you know how sensitive your skin can get ..right ??? Lol
Well this takes down the redness quickly and soothes the area.
As for stubborn acne, just apply a small amount to the area a couple times a day & your pimple will shrink ..it really works ✅
Smh 4.
179 reviews
Beauty Junkie Expert Level 3
Well this was an on spot treatment that i had used when i did have acne problems . It did help , along with drinking allot of water . It burns when u first put it on and overtime it creates a barrier for your skin so that no bacteria can enter through . Over time it reduces the size of the pimples and it reduces the redness . Eventually crusting and coming off . It does contain salicylic acid so if u have extremely sensitive skin this may not be for u
Caitlin M.
21 reviews
Beauty Junkie Expert Level 1
Great product, perfect for pesky pop ups! Has a thick gel consistency which is ok for wearing to bed, as I apply mine over night, and 8/10 times I find it takes away redness and bump size significantly, however sometimes does not work at all. I keep purchasing this as it is the best spot treatment i've tried to date. However, I find after using for 2 or 3 days its fine, but also works good on mass areas of imperfections!
3 reviews
This spot treatment is probably the only treatment that has helped my acne. It works wonders for your skin.. the results are shocking, it does exactly what it claims. I have been using it for a really long time continiously, But now my skin just burns when I apply it on any pimples. It also really really dries out my pimples and the surrounding area. So it looks awful when I put my makeup on because you can see flaky dry patches. Even though I do have occasional pimples that come and go, I am officially gonna stop using this because I am tired of the dryness! I do recommend it though. I personally just think this is not good for long term use. 
Patricia-Ann Q.
Ottawa , ON
58 reviews
Beauty Junkie Expert Level 2
i do not have an acne / oily type of skin but occasionally, especially during my period, i will get a spot here and there. And when I do, this the treatment that I immediately go to! it is truly effective, i use it twice a day and i do not put make up on it. the gel form is amazing as it is invisible so very wearable even during day time. i use it two consecutive days and then acne is gone! 
Ruby T.
Croxley road , Kings Langley
190 reviews
Beauty Junkie Expert Level 3
not too impressed with this acne treatment after the raving comments from my friends but obviously this is just my experience/skin type! I did not see a huge difference when applied, only the fact the redness faded after a few days however did nothing in terms of reducing size.
Brai P.
London, ON
7 reviews
i found that this spot treatment dried my combination skin, although it did stop the pimple from getting worse after a about two uses. i would recommend to someone who doesn't have sensitive skin, but my skin is sensitive so it wasnt quite the right product for me.
Taylor C.
Kirkcaldy , Scotland
46 reviews
Beauty Junkie Expert Level 2
This product I used a couple of years back for the first time,im not a repeat user of this product but if I’ve got it I’ll yous it, its gentle on my face and friendly but I wouldn’t go out my way to buy it again only because it never really made a difference for me
Katie M.
Blaydon on tyne , Ne 21 6eh
6 reviews
Beauty Junkie Expert Level 1
For my skin type this product seemed to not work so well for me, I had high hopes but my sensitive skin had a tendency of breaking out even more when using spot treatments that aren’t aimed for people with sensitive skin. I have a friend how ever who also used this product and it worked absolute wonders, so if you don’t have sensitive skin I’d recommend giving it a try
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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