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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,328 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10328)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Alexandria M.
39 reviews
Beauty Junkie Expert Level 1
I've been using this acne product for a while now just in case I get a pop up blemish/pimpl. It works really well, and greatly reduced the acne spot within a day!
Paola A.
Miami, FL
107 reviews
Beauty Junkie Expert Level 2
This is amazing for MASSIVE spots, reducing the size dramatically overnight. But if you have sensitive skin it will make it quite red so make sure you splash your face with cold water after use. It does irritate your skin for 10 minutes. It does burn, but it's worth it. Another thing to add is that it is not invisible. It makes your spot shiny and if you add enough, it will cause these odd white patches which is the spot gel sinking into your skin. I wouldn't wear this under makeup. Also, it peels off your face so if you're going to go out without washing it off your face then make sure you don't have any white peelings on your face. It also smells sweet, yet solvent-y. It does work, but you do have to work your way around the redness and the fact that it looks obviously there. That's not that much of a price to pay for clear skin. I have also noticed that the gel causes whiteheads to form prematurely. So if you need to go out spot-free in a couple of days, why don't you put this on every four hours, wash and done your face 3 times a day and apply this straight after. This is what I'm doing and my spots seem to be almost gone! And, spots that were sore yesterday are now painless! It doesn't work for everyone, so just buy one tube and give it a shot. The tiny tune will probably last 2 weeks and be sure to give it a proper trial. Maybe take a picture before and after 2 weeks to see how clear your skin had become? Some people think that this has made their skin more spotty, and I think this is because sometimes it causes crustiness and redness that can be mistaken as a new spot. I have terrible dry skin and sometimes oily skin so this has actually helped both of these! I haven't gotten dry skin since I started using it. I usually have to scrub and peel dry flakes off my skin every 2 days of I want my skin to be baby smooth. But it has been more than 2 days and it's completely fine! I really recommend this!
Shana C.
31 reviews
Beauty Junkie Expert Level 1
This product is something that was created by the gods. I don't get too many pimples but when I get them they're huge and obvious . I can always feel my pimples coming and the last time I did I knew it would be a big one, I did everything I could to clean my face but nothing focused in enough to stop the pimple. I was really desperate so I raided my sisters bathroom and found this product, I was willing to try anything so I used it. The next day the pimple had reduced and was a million times less obvious. I went out and bought my own ADVANTAGE Acne Spot Treatment and have been using it for a few months now. This thing has made it so I'm basically acne free and has made my life a million times better. For spot treatment I would definitely recommend this product.
Jen R.
South Ayrshire, Ayr
93 reviews
Beauty Junkie Expert Level 2
This product is a life saver when you wake up with a big annoying spot, I use it each night before I go to bed and I love waking up to see the results in the morning. My spots appear to be less red and have gone down in size. I tend to find it works better on older spots or ones that have been popped. Can be quite irritating and drying for those with sensitive skin - often leaves me with red marks but dries out and makes it easier to apply makeup on top.
Vanessa R.
Kawartha Lakes, CA
136 reviews
Beauty Junkie Expert Level 2
'm going to make this a little personal but it's a great way to prove how well Clean & Clear's Spot Treatment works. I had gone through one of the toughest break-ups about three months ago. With all the stress and disappointment my skin blew up with the worst acne ever. I tried everything, but it was an infection on my face that just seemed to be spreading and growing from one side to the other. I was embarrassed to go out and I just kept mucking makeup on my face, which mainly made it worse.My confidence was gone. Finally, after a lot of blood, sweat, and tears my roommate suggested Clean & Clear's Spot Treatment. After using it one day I was sold
Janelle W.
13 reviews
Beauty Junkie Expert Level 1
I have used this product for years. I have had mild to moderate acne over the years and this is my go to for skin flare ups. I find that it reduces redness within a few hours as well as the size my pimples. I don’t find it is super effective for my boyfriend who has recurring large pimples though. However, I think it’s completely affordable at under $20 and it doesn’t leave me with any skin reactions like many popular acne products including Proactiv. If you have taken the top off of a pimple or there’s any kind of broken skin before application it will sting briefly so be aware of that! The smell is also not offensive which I love.
Missy A.
Calgary, AR
145 reviews
Beauty Junkie Expert Level 2
I have had a few breakouts and large red pimples that would stay for weeks so I did some research on good products to use to clear that up ,and I came across the Clean and Clear Acne Spot Treatment.
I’ve been using it once a day for a week and I have noticed that my pimples have gone down in size and the redness reduced a bit. But I’ve also noticed that my skin has been peeling and the product has made me breakout more on different areas of my face. Didn’t help much to be honest. So I do not recommend.
shaima 🌸.
46 reviews
Beauty Junkie Expert Level 1
i'm beauty blogger ; my name is beautys_shaima
This is my favourite hair styler for smaller tight curls, I feel like you could create waves or loose curls with this wand but I struggle to do this. I love the style of the wand and feel it’s easy to use, the wand comes with a heat protection glove to avoid burns when wrapping you’re hair around the wand. I feel you don’t have to hold you’re hair in the wand for long at all so there’s less damage to you’re hair. The curls stay in for hours even over night in my hair.
Vanessa c.
152 reviews
Beauty Junkie Expert Level 2
Best . Sh$t. Ever !!!! 💕

If you suffer from acne or have that occasional monthly breakout ...this is your new best friend .

This little guy also helps with irritation from facial waxing , so if you’ve had brow waxing or your upper lip done, then you know how sensitive your skin can get ..right ??? Lol
Well this takes down the redness quickly and soothes the area.
As for stubborn acne, just apply a small amount to the area a couple times a day & your pimple will shrink ..it really works ✅
Smh 4.
179 reviews
Beauty Junkie Expert Level 3
Well this was an on spot treatment that i had used when i did have acne problems . It did help , along with drinking allot of water . It burns when u first put it on and overtime it creates a barrier for your skin so that no bacteria can enter through . Over time it reduces the size of the pimples and it reduces the redness . Eventually crusting and coming off . It does contain salicylic acid so if u have extremely sensitive skin this may not be for u
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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