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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,307 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10307)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Rachel T.
Fuquay Varina, NC
8 reviews
I keep this on hand to help take care of random blemishes. It usually works well, but depending on the blemish size/location I may not notice much difference. Be careful not to use too often as to not dry out the skin
Katie W.
Manassas, VA
130 reviews
Beauty Junkie Expert Level 2
This is a very good product. It clears up my blemishes but not too harshly and does not dry out the skin around it. I would recommend it to anyone that has occasional blemishes to put on over night. I would but again.
Stephanie T.
Mission, TX
134 reviews
Beauty Junkie Expert Level 3
Works pretty great ! Gets rid of redness and bumps within 1-2 days ! Tingles a little bit but feels nice on the skin . It's affordable too which is great and it's easy to use . I recommend to anyone who wants a quick spot fix
Simply S.
18 reviews
It works on certain pimples for me only and doesn’t work as well as other treatments. It makes my pimple itch and feel hot but for some of my family members and my friend, it is their favorite spot treatment for zits.
Sophie A.
Roswell, GA
36 reviews
Beauty Junkie Expert Level 1
It’s just okay in my opinion. There are better spot treatments around the same price range than this one. I don’t think it works super well or shows any huge differences the next day. Probably wouldn’t buy it again.
Rachel F.
Palm Coast
63 reviews
Beauty Junkie Expert Level 1
Doesn’t dry my skin out and kind of gets rid of the pimple. More or less just lessons it. Doesn’t get rid of it as fast as it claims to though. Don’t think I buy it again. I feel there are better products out there.
Jessica B.
12 reviews
Amazing product! This always works no matter the size of my spot. I clean my face and put this on before my moisturizer and the next day it’s half the size it was
12 reviews
Beauty Junkie Expert Level 1
I actually really like this product because it works I would say this product only works if you have little pimples and not big ones and this doesn’t work for acne scars only smaller pimples. It depends on your skin condition so this might work for you.
Molly B.
18 reviews
Beauty Junkie Expert Level 1
I can put this on a baby just-starting-to-look-like-a-bump pimple at night and by morning it’s dried up! Also I like putting this on ingrown hairs because it dries them up and keeps them from turning into infection.
Valerie L.
22 reviews
Beauty Junkie Expert Level 1
I had heard great things about this product from friends but when I used it on pimples it did not seem to help them at all. I thought that this spot treatment would at least dry them out but that was not the case.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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