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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,292 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10292)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Nicol D.
21 reviews
Beauty Junkie Expert Level 1
Absolute favorite acne spot treatment. I keep it in my purse and can even apply it over makeup and notice a different when I take my makeup off. It works fast and it doesn't sting when I personally apply it.  
Alana T.
153 reviews
Beauty Junkie Expert Level 3
i loved this product and want to repurchase. very nice packaging, and comes in a travel size tube, it’s a little harsh but it’s to be expected in my opinion with a spot treatment for acne, other than that i have nothing bad to say about the product. LOVE IT!
camille D.
Herkimer , NY
142 reviews
Beauty Junkie Expert Level 4
I use this as a back up my face care routine sucks to say the least but this product seems to reduce redness and “ugly”pimple looks within just a couple of days without drying out my face! I love the easy to use design!
Sapphire D.
Vineyard, UT
151 reviews
Beauty Junkie Expert Level 2
This product is simply amazing. If you haven’t tried it you need to! The packaging is nice and i seriously love how gentle it is on my skin. It totally was worth it and I buy this all the time! Definitely give it a try!
Nafas G.
Alexandria , VA
75 reviews
Beauty Junkie Expert Level 2
I’ve been using this since my high school days . I believe this is perfect in budget and most effective treatment you can have . Walmart is best place to locate it . Just s tiny bit on the spot and next days it’s gone .
Destiny B.
69 reviews
Beauty Junkie Expert Level 2
I think that this works a lot better than persa gel 10. It’s very effective at reducing the size of a blemish. Definitely a good spot treatment especially if you’re not looking to spend a lot of money on treating acne.
Laila A.
66 reviews
Beauty Junkie Expert Level 1
I’m currently using this and I have to apply it several nights in a row before the pimple is gone. Yes I can see it slowly going down but I just want fast results.
Cree R.
Madison, WI
32 reviews
Beauty Junkie Expert Level 1
Not the best but not the worst. It take a few days for it to really work, I put it on every morning and night, sometimes the afternoon. Very good price I would say, but doesn’t get the job done as fast as I would like.
Paige B.
Greenville , OH
99 reviews
Beauty Junkie Expert Level 2
I love this gel. I have used this for years and whenever I have a really bad breakout I just apply this gel usually once or twice and the acid in the gel pretty much dissolves the breakout in just a couple of days 2-3.
Stephanie T.
Mission, TX
134 reviews
Beauty Junkie Expert Level 3
Works pretty great ! Gets rid of redness and bumps within 1-2 days ! Tingles a little bit but feels nice on the skin . It's affordable too which is great and it's easy to use . I recommend to anyone who wants a quick spot fix
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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