Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,292 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10292)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Dalila A.
13 reviews
I absolutely love this product, I put it overnight on all of my scarring on my face and overtime it dries out the layers of skin so that the scars fade. I also put it when I pop a pimple to dry it out and it is less likely to scar that way!
Haley F.
23 reviews
Beauty Junkie Expert Level 1
I always have a tube of this in my purse or with my makeup for whenever I might break out. It works really well for me and helps too get rid of unwanted blemishes!!
Emily B.
Greenville, SC
60 reviews
Beauty Junkie Expert Level 1
This is my favorite spot treatment!! This Clean and Clear product has worked more effectively for me than more high end products. Gel like texture does not dry out the skin. Put on an acne spot overnight and it is virtually gone by the morning.
Patty M.
Clarksville , TN
64 reviews
Beauty Junkie Expert Level 3
Clean and clear has been a go to brand for me since I can remember buying facial cleansing products ! I love the spot treatment because I don’t feel like I need to expose my entire face to products if my entire face isn’t having a moment ! Lol
Angie R.
Somerset, KY
190 reviews
Beauty Junkie Expert Level 3
This team did not work for me at all. I really saw no difference what so ever. My daughter used it as well and there were no changes at all. Complete waste of our money. Completely made me think twice about ever buying Clear & Clear again.
Selena C.
Bluffton, SC
82 reviews
Beauty Junkie Expert Level 2
I do not struggle with acne besides those one or two that decide to come out when on my menstrual cycle. When I get those one or two pimples I use this product and I feel it gives me instant results I definitely recommend it is non drying.
11 reviews
This does clear on the spot pimples but if you use it too much or leave it on too long it will burn your skin and leave a scar. The price is great and it is very effective just be careful so you don’t burn your skin.
Amanda M.
Burkburnett, TX
32 reviews
Beauty Junkie Expert Level 1
Personally it over dried the spots I used, caused major redness to the area surrounding the pimple it self . It just didn’t work for me, but I’m sure it will for someone else. Decent price and I’m sure it works, just not for my picky skin!
Emilie M.
42 reviews
Beauty Junkie Expert Level 1
Works pretty well and easy to use. I applied every night until blemishes went away. Was effective but didn’t dry out my skin so that was nice. The little tube makes it easy to squeeze out a precise amount. Clean & Clear® Advantage® Acne Spot Treatment
Ella S.
Miami Beach, FL
167 reviews
Beauty Junkie Expert Level 2
this stuff is my GO TO every single day. i put this on any spots i might have before i go to bed and everything disappears in the morning i swear this product is like magic!! i one hundred percent recommend this to you if you have acne issues!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

BackInfluenster Cashback
Clean & Clear® Advantage® Acne Spot Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.