Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,717 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,701)
Q&A (493)
Media (124)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Destinee L.
65 reviews
Beauty Junkie Expert Level 1
I have hear some good reviews so I thought I’d take it a try and sadly to say I wasn’t happy with my experience
Ashley P.
207 reviews
Beauty Junkie Expert Level 4
This is one of the best drugstore options for a spot treatment. It dries the pimple out without over drying it.
Elaine R.
146 reviews
Beauty Junkie Expert Level 3
This is a great acne spot product! It really works! You can use it specifically where the spots are locate it!
Deichae N.
St. George
101 reviews
Beauty Junkie Expert Level 2
Just a cream that didnt dry it out or anything. Just a cream on a zit. Didnt do anything. Wouldnt buy it again.
Kerry Ann Z.
Manhattan, IL
127 reviews
Beauty Junkie Expert Level 2
This treatment is like magic. It shrinks pimples super quickly, almost overnight. It isn't super drying either.
Irene P.
23 reviews
Beauty Junkie Expert Level 1
Purchased at: Walgreens
When you have s pimple add this and over nights it will almost be gone. The swelling will not be there anymore
Sabdy A.
Hamilton , OH
27 reviews
Beauty Junkie Expert Level 1
In 3 weeks this made my acne either go away and make it very small! It also made a lot of my blemishes go away!
Nancee C.
South Salem
16 reviews
This baby will ZAP that pimple RIGHT off of your face. Amazing product. I would definitely recommend to anyone
Haelei K.
Roosevelt, UT
259 reviews
Beauty Junkie Expert Level 4
It worked if you used it 2 days in a row religiously but not if you tried to use it as a one day spot treatment
Autumn C.
27 reviews
Beauty Junkie Expert Level 1
the smell of this product is really intimidating. the product stings some when you put it on but it works fine. 
Ashley S.
30 reviews
A little bit, but I started using it once a day and then increased use. I also used more moisturizer.
Shaelyn W.
67 reviews
Beauty Junkie Expert Level 4
Really want to try this. Is it a well working product?
Johanna R.
7 reviews
Can I use this product over makeup? I only really use it when I’m home and not going anywhere but I’m not sure if it would work with makeup.
Charl L.
212 reviews
Beauty Junkie Expert Level 3
Does this actually work? How long until you see results?
Jazzminn G.
Laredo, TX
102 reviews
Is this good?

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