Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,523 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10523)
Q&A (464)
Media (121)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Nicole B.
Bradenton, FL
109 reviews
Beauty Junkie Expert Level 1
It didn’t work well for me personally. I do feel like it’s more gentle than some other spot treatments though.
Gina L.
9 reviews
This product dries my skin out too much but sometimes it is very effective in eliminating my acne. Hit or miss
Sarah J.
United states
38 reviews
Beauty Junkie Expert Level 1
Clean and clear keeps my blemishes at bay and keeps my skin radiant! It's my go to product for spot treatments!
Shaina R.
Bath, NH
113 reviews
Beauty Junkie Expert Level 3
Joke.....such a waste of money. It really dries out your skin. Dries out every inch of skin except the pimples.
Allison C.
Smyrna, GA
32 reviews
When I do have acne, this is a great zapper that helps diminish the size and redness of zips when they pop up!
Angelic M.
23 reviews
Beauty Junkie Expert Level 1
I first got this in highschool I would get ache here and there and this takes care of the issue works wonderful
Traci T.
West Palm Beach
6 reviews
Beauty Junkie Expert Level 1
Works well at drying out the small blackheads that occasionally bother me more than my aging skin. . . . . . .
Rachel B.
50 reviews
Beauty Junkie Expert Level 1
I've used this since high school and I graduated almost 5 years ago and I still buy this product and I love it
11 reviews
Has a pretty good smell and works well overnight to get rid of any pimples before the morning. Would recommend.
Kelly A.
122 reviews
Beauty Junkie Expert Level 2
One of my favorite spot treatments. Isn’t over drying and works well. Affordable and gets rid of stubborn acne
Karene L.
Orlando, FL
5 reviews
Does this product work for every skin type?
Patricia T.
Detroit, MI
1 review
Does this work well? I have used a few products over the years for my acne, and it just keeps coming back.
Denise G.
New London, CT
7 reviews
I have acne problems that have recently accur. Is this product good? Also is it okay to use for sensitive skin?
Sierra F.
1 review
How well does this fight off mild acne? And how quickly
Kelsey W.
Liberty Lake , WA
16 reviews
Looking for a quick spot treatment remedy for pimples. How long does this product need to stay on to take affect?

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