Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,537 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10537)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Haley F.
23 reviews
Beauty Junkie Expert Level 1
I always have a tube of this in my purse or with my makeup for whenever I might break out. It works really well for me and helps too get rid of unwanted blemishes!!
Angie R.
Somerset, KY
190 reviews
Beauty Junkie Expert Level 3
This team did not work for me at all. I really saw no difference what so ever. My daughter used it as well and there were no changes at all. Complete waste of our money. Completely made me think twice about ever buying Clear & Clear again.
11 reviews
This does clear on the spot pimples but if you use it too much or leave it on too long it will burn your skin and leave a scar. The price is great and it is very effective just be careful so you don’t burn your skin.
Selena C.
Bluffton, SC
82 reviews
Beauty Junkie Expert Level 2
I do not struggle with acne besides those one or two that decide to come out when on my menstrual cycle. When I get those one or two pimples I use this product and I feel it gives me instant results I definitely recommend it is non drying.
Carrie B.
42 reviews
Beauty Junkie Expert Level 1
Love this little tube of miracles! I have been using it for years on small pimples that show up or I can feel. Best to use it at night and in the morning they are always significantly smaller or gone! It doesn’t burn my skin or make my skin peel either like some others have done
Kaley J.
Russellville, AR
27 reviews
Beauty Junkie Expert Level 1
I love this drugstore acne spot treatment. It’s very affordable and worked well for me. I would see instant results in less than 24 hours. It’s not too harsh but does have a slight sting when applying directly onto a problem spot. I also really like the smell of it!
Kiana W.
6 reviews
This is okay I mean i don’t really see a difference in my acne however it does even out my skin tone and texture and makes me skin very clear but I have to use another acne wash to actually clear my acne but otherwise it’s a good product
Jessica M.
55 reviews
Beauty Junkie Expert Level 1
Purchased at: Walmart
I really love this product and it really works for my skin. I just need to apply at night before sleep and in the next day is much better. I would say it takes 2-3 days to be completely done. The price is great and it lasts a long time.
67 reviews
Beauty Junkie Expert Level 1
This is a great spot treatment! It doesn't seem to irritate my sensitive skin, but completely eliminates pimples in just a few days with daily use. All it takes is a tiny amount once or twice a day (I use it after cleansing and moisturizing) for a few days, and the spot completely disappears.
Ruffa F.
Las Vegas, NV
35 reviews
Beauty Junkie Expert Level 1
Purchased at: Walgreens
This product is totally affordable and does it job well! It dries out any breakouts you’ve got on your face and you can wake up the next day with a happier face. I would totally recommend this to others for the price point and the quality of a job that it does as well. I love it!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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