Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,541 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10541)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Natalie F.
228 reviews
Beauty Junkie Expert Level 4
This didn't really work like I expected it to. I rarely get pimples but I was hoping this worked better than it did.
Heather C.
Alpharetta, GA
24 reviews
This stuff really does work but only if your skin reacts salicylic acid. Otherwise benzyl peroxide is your best bet.
adri P.
129 reviews
Beauty Junkie Expert Level 2
i’ll use this a few times on my face when i have a pimple coming and 9/10 it won’t surface due to the spot treatment
Kim S.
63 reviews
This stuff doesn't do anything for my rare breakouts. I usually don't breakout but this stuff doesn't help it at all
ashley m.
45 reviews
This spot treatment really dried out the area of imperfection and reduced its size significantly by the next morning
Joelene A.
North Port, FL
13 reviews
The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
Harlie S.
Honea Path
17 reviews
Beauty Junkie Expert Level 1
It works amazingly gets rid of acne before it shows up and it’s very affordable. I definitely recommend this product
Lauren B.
Harrington, ME
84 reviews
I would not use for all over problem acne, but I loved it as an overnight spot treatment. Didn't dry my skin out. :)
Molly M.
67 reviews
Beauty Junkie Expert Level 1
I bought this for my daughter who has extremely sensitive acne prone skin. It’s ok at best doesn’t work great though.
Haleigh L.
Logan, WV
107 reviews
Beauty Junkie Expert Level 4
I used to use this before I switched to another Clean & Clear acne medicine, but if I had to use this I still would.
Noor A.
87 reviews
Beauty Junkie Expert Level 3
Does it dry out the face?
Diana R.
42 reviews
Beauty Junkie Expert Level 1
Does it irritates the skin?
Amanda L.
Winchester, VA
2 reviews
I have been wanting to try this product for awhile, how well does it work for current acne, as well as acne scars?
Jazzminn G.
Laredo, TX
102 reviews
Is this good?
Diana R.
30 reviews
Beauty Junkie Expert Level 1
Is this a good product? I have struggled with acne for years now. And nothing I have used works.

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