Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,561 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10561)
Q&A (464)
Media (122)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Beatriz Q.
Houston, TX
16 reviews
Acne spot on treatment is amazing. Place it on as soon as I notice a pimple. By the next day is has reduced in size.
Jasmine K.
48 reviews
Beauty Junkie Expert Level 2
Works great! I use it whenever I feel a pimple under the skin and it disappears within two day! Definitely recommend!
Callie M.
142 reviews
Beauty Junkie Expert Level 3
This is my favorite thing to use for treating pimples. It dries the pimple out for a faster clearing of the breakout.
Jordan W.
251 reviews
Beauty Junkie Expert Level 3
I tried this spot I didn’t help at all it made face worst I had a new face product I was hoping it was going to work.
Jean M.
San Jose
15 reviews
Great for tackling pesky spots of acne. Works fast and can be put on just before applying foundation and moisturizer!
Kristina B.
31 reviews
Beauty Junkie Expert Level 1
THIS IS AMAZING!!! Thankful that I came into contact with this! This product has saved the day for me multiple times!
María E.
Miami, FL
282 reviews
Beauty Junkie Expert Level 4
I used many years ago in another presentation, but it did not work for me. Smells a little alcohol (what worries me)
Liesha T.
22 reviews
Beauty Junkie Expert Level 1
I have been using this product faithfully! You see results within a day or two. It can sting a bit but it goes away.
Jackie F.
117 reviews
Beauty Junkie Expert Level 3
Works wonders. I had acne in high school and I would put this one and by the next day it was gone or almost all gone.
Ambreen A.
59 reviews
Beauty Junkie Expert Level 4
I use this when I feel like a pimple is wanting to come out. It dries it up and my problem goes away within two days.
Shaelyn W.
67 reviews
Beauty Junkie Expert Level 4
Really want to try this. Is it a well working product?
Ashley S.
30 reviews
A little bit, but I started using it once a day and then increased use. I also used more moisturizer.
Johanna R.
7 reviews
Can I use this product over makeup? I only really use it when I’m home and not going anywhere but I’m not sure if it would work with makeup.
Jazzminn G.
Laredo, TX
102 reviews
Is this good?
Chae W.
Las Vegas, NV
6 reviews
is this product ok for sensetive skin?

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