Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10565)
Q&A (464)
Media (122)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Marilisa N.
Virgilina, VA
23 reviews
This brand is really good from my skin. The acne goes way when I use this. It goes way really fast. It's good for the skin. ☺️
Lizzie D.
Dix Hills
12 reviews
It definitely helps my acne but does not fully get rid of it. For someone who has less severe acne than me it may work better.
Aylin A.
92 reviews
Beauty Junkie Expert Level 4
this product is so good. It got rid of my huge pimples overnight. I really recommend this for anyone who has trouble with acne.
Amanda H.
Normalville, PA
43 reviews
Beauty Junkie Expert Level 1
I've always had fairly clear skin but when I get a breakout I have a hard time clearing it up until I tried this it works quick
Ciara W.
Gainesville, GA
208 reviews
Makes my skin break out so bad!
And look so red and irritated I can not use this! If you have sensitive skin I do not reccomend
Tracy J.
22 reviews
My go-to sport treatment when a blemish flares up. Drying, yes, but I’ve found it works even when I layer moisturizer over it.
Britney M.
9 reviews
Product is great for small breakouts. But, takes longer to heal larger bumps. Gives off a burning sensation when first applied.
Jessica-Grace D.
39 reviews
Beauty Junkie Expert Level 1
I don’t break out to bad but when I do it’s bad so I got this hoping to help my acne and I’m so sad to say I saw no difference.
Katie H.
10 reviews
As small as it is, it is definitely worth the money. You don't need a lot and it shrinks large zits over night for me. Love it!
Lyla A.
110 reviews
Beauty Junkie Expert Level 2
I put this on when I get that tender feeling when a pimple is brewing under the skin. Most of the time this zaps it overnight.
Sierra F.
1 review
How well does this fight off mild acne? And how quickly
Mikayla H.
577 reviews
Beauty Junkie Expert Level 4
Has anyone tried this?? Is it effective?
Kelsey W.
Liberty Lake , WA
16 reviews
Looking for a quick spot treatment remedy for pimples. How long does this product need to stay on to take affect?
Kristen B.
Pembroke, MA
21 reviews
I'm really interested in trying this but I have super sensitive skin, anyone else have sensitive skin and get good results from this??
Shantanell R.
Halifax, VA
17 reviews
Beauty Junkie Expert Level 1
Does this dry out the acne ?

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