Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,527 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10527)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kyra H.
32 reviews
Beauty Junkie Expert Level 1
I've never saw a huge difference after using this product. I wouldn't recommend to a friend. It's expensive for a small amount
Andrea R.
Rockford, IL
139 reviews
Beauty Junkie Expert Level 4
This product irritated my face and just made the spots I applied it to turn even more red. It also burn when I applied the gel.
Emilia L.
34 reviews
It worked the first few times I used it but became less effective as time went on. While it is cheap, I wish it worked better.
Jessica Z.
brooklyn, NY
28 reviews
Beauty Junkie Expert Level 3
This is great for that one pimple that won't go away. I used it at night, and the next morning, it was almost completely gone.
Mercedes S.
34 reviews
Beauty Junkie Expert Level 1
Love this little guy I use this before putting on makeup on acne or at night and leave on over night. Does really shrink them.
J_Fresa G.
Harrisburg Pa
14 reviews
God bless who ever created this product ((: seriously works instantly !! it reduces size redness & go away in a day maybe two.
Charlotte Q.
Lansdale, PA
69 reviews
Beauty Junkie Expert Level 2
I use this when I get big pimples before I go to sleep and the next day I see that my pimple spot has decreased significantly.
Brianna Y.
Philadelphia, PA
7 reviews
Great product that definitely works for my oily, acne-prone skin! Works extremely well at reducing size and redness over night!
Wendy C.
87 reviews
Beauty Junkie Expert Level 1
I rarely breakout but when I see a spot coming, a small dab of this usually wipes it out overnight. One tube lasts a long time.
Michelle W.
Henderson, NV
15 reviews
Doesn't dry my skin, takes a little longer than I hoped to rid of the break out. Doesn't smell weird, a little goes a long way
Karene L.
Orlando, FL
5 reviews
Does this product work for every skin type?
Patricia T.
Detroit, MI
1 review
Does this work well? I have used a few products over the years for my acne, and it just keeps coming back.
Denise G.
New London, CT
7 reviews
I have acne problems that have recently accur. Is this product good? Also is it okay to use for sensitive skin?
Sierra F.
1 review
How well does this fight off mild acne? And how quickly
Kelsey W.
Liberty Lake , WA
16 reviews
Looking for a quick spot treatment remedy for pimples. How long does this product need to stay on to take affect?

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