Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,521)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Bronika T.
42 reviews
Beauty Junkie Expert Level 1
This is an amazing product. I put it on at night on the effected skin and I wake up with the spot extremely smaller than it was before.
Bailey H.
Covington , GA
65 reviews
Beauty Junkie Expert Level 4
This product was a life saver in high school for me! It was a little intense since I have very sensitive skin but it got the job done!
Haley R.
Durand, MI
51 reviews
Beauty Junkie Expert Level 2
I really like this acne product, as soon as I feel a pimple coming I put this on and in a couple days it’s all healed up and dried out.
Kayla B.
107 reviews
Beauty Junkie Expert Level 2
Works great for spot treatment but it is kinda pricey for such a little tube. It forms like a film on the skin to help dry out pimples.
Mandie P.
Indian Trail, NC
66 reviews
Beauty Junkie Expert Level 1
This worked very well for me. I applied a small amount to a pimple and it dried it up within 24 hours. Would definitely use this again!
Drew S.
Canton, IL
68 reviews
Beauty Junkie Expert Level 1
This is probably one of my favorite Clean n' Clear products. I use it at the first sight of a zit and it helps get rid of them quicker!
Megan M.
Mission Valley
20 reviews
Beauty Junkie Expert Level 1
It definitely works very well. I have used this for a while. It doesn't burn or stink like some spot treatments so that's a plus. 
Beatriz V.
San Diego, CA
399 reviews
Beauty Junkie Expert Level 4
This product is amazing ! I see results within 2 days of using the product ! Super cheap and I recommend everyone with all skin types .
Megan S.
Cedar City
26 reviews
Beauty Junkie Expert Level 1
Love love love this I put it on the acne spots and leave on it and it burns a little bit I love that feeling cause I think it's working
Hannah C.
13 reviews
Beauty Junkie Expert Level 1
Just got it a week ago and it’s already working well on my acne. I had a recent weird breakout and this helped to get it under control.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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