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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,281 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10281)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kayla S.
Eagle, NE
226 reviews
Beauty Junkie Expert Level 3
I tried this clean and clear acne treatment a couple years ago. It smells great but didn't clear up my blemishes as quickly as I expected.
Taylor Y.
12 reviews
Whenever I get a spot I please put this on morning and night. I really do feel like it helps get rid of my spots. I'm on my third tube now!
Stefanie S.
Orem, UT
187 reviews
Beauty Junkie Expert Level 2
This is a great product to put on your acne but not all over your face! Great for that specialized treatment! #cleanandclear #acnetreatment
S•A•B•R•I•N•A M.
88 reviews
Beauty Junkie Expert Level 2
This product is beyond amazing. If you have a pimple or blemish (new or  existing) this product will get rid of it. It works so fast!
Selena V.
Centereach Ny
22 reviews
Beauty Junkie Expert Level 1
This product does work but if you have sensitive skin you have to be careful with it ! I chemically burned my skin a few times with this .
Kassandra H.
Riverton, IL
113 reviews
Beauty Junkie Expert Level 4
Sometimes this works for me and sometimes it doesn't. I guess it's the luck of the draw. I like that it's not too strong of a scent though.
robyn M.
27 reviews
Beauty Junkie Expert Level 1
If i had a terrible pimple this was my go to stuff to get rid of it. It has always worked for me. I have used this for years and i love it
Monique B.
Farmville, VA
61 reviews
This is hit or miss with me. It also burns and dries out my skin pretty badly. I use it in combination with other products to make it work.
Ashleigh O.
Altamonte Spg, FL
18 reviews
Beauty Junkie Expert Level 1
I didn't personally have luck with this product. At least not in terms of helping to prevent or treat a breakout faster than using nothing.
Courtney G.
Myrtle Beach
56 reviews
Beauty Junkie Expert Level 1
This product is amazing I have not been braking out and my skin has not been oily. I am using it right now and it’s my new favorite thing.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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