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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,274 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10274)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Allison T.
38 reviews
Beauty Junkie Expert Level 1
If I out this on at night, when I wake up in the morning there has been immense clearing. I recommend this for anyone looking for fast results!
Antonia W.
Citrus Hts, CA
196 reviews
Beauty Junkie Expert Level 4
I like this to spot treat. I use at night. It works well and does what it should do after a few nights with it one my problem area is gone too.
Erica P.
San Antonio
81 reviews
Beauty Junkie Expert Level 2
A must have for an emergency breakout! Fast and effective. If you catch a pimple in time and apply this, it usually knocks it out in 24 hours.
Hannah S.
Tualatin, OR
59 reviews
Beauty Junkie Expert Level 2
Good for teenagers but it just didn't work for me. It stung my sensitive skin. And didn't get rid of my acne. Over all I wouldn't use it again.
Casandra K.
44 reviews
Beauty Junkie Expert Level 1
This is like the best acne product! I first got it in a kit with other products and I have not stopped using it! It literally works overnight!
Sierra B.
Connelly Spg, NC
49 reviews
Beauty Junkie Expert Level 1
I use this after I extract a blackhead/ white head using my tool and the next day you can see a visible difference in the size of the blemish.
Emily H.
9 reviews
Has been my go to for 10 years. Less effective on my skin than it used to be but I think it’s my skin evolving and the product is still great.
Marissa F.
San antonio, TX
106 reviews
Beauty Junkie Expert Level 1
Love this spot treatment! I tend to breakout during my time of the month and when I feel a spot coming I also reach for this! Quick and easy :)
Madison S.
San Jose
46 reviews
Beauty Junkie Expert Level 1
Dies up acne pretty fast. Plus it helps shrink blackheads. It hasn’t gotten rid of them yet but I will give an updated review if it ever does!
Lizbeth M.
27 reviews
Beauty Junkie Expert Level 1
It burns when you apply it but that’s the obvious, it’s really cheap. It really works when you apply it over night and I like that it’s clear.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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