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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,325 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10325)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
34 reviews
Beauty Junkie Expert Level 1
I use this when I have a pimple that I need gone quickly! I feel like it really helps dry out the pimple and is not near as noticeable the next day.
30 reviews
Beauty Junkie Expert Level 1
My favorite spot treatment to use overnight! Can leave dry spots if you use multiple times in a row but makes the pimple go away quicker than usual.
Sharie W.
Oklahoma City
37 reviews
Beauty Junkie Expert Level 1
This is a miracle worker. If I wake up in the morning with a new pimples I just pop this cream on it and a few hours later the pimple is going down.
Kassi C.
20 reviews
I absolutely love this. It's really great and it's so cute being little and it's packaging. I love what it's done to my face . It does great wonders.
Lauren G.
4 reviews
Love this! It worked great for me when nothing else would and didn't irritate my very sensitive skin!! It also smells great and dries fast, win/win!!
Arisel B.
84 reviews
Beauty Junkie Expert Level 1
Very useful. It does burn a bit if you have an open pimple. But this is a very helpful prodcut that will get rid of any annoying pimple you may have.
Megan H.
Fenton, MO
31 reviews
Beauty Junkie Expert Level 3
This acne spot treatment is awesome. I actually carry it in my purse so if i feel a pimple coming in a dab it on there and I know it'll be gone soon.
noemi R.
9 reviews
I apply a tiny amount over a dark acne spot and in no time the dark spot is gone. Before I apply this I make sure to follow my face cleanse routine.
Liz M.
Dickson , TN
18 reviews
Beauty Junkie Expert Level 1
Este producto funciona de maravilla yo lo usado por algunos años y la verdad es que siempre tengo problemas con el acne regresó a él y regreso a el.
Miranda M.
Maplesville , AL
44 reviews
Beauty Junkie Expert Level 1
This stuff really works and clears up a pimple. It’s inexpensive and also this small tube lasts a while because you only have to use a small amount.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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