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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,315 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10315)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Angela M.
Brooklyn, NY
36 reviews
Beauty Junkie Expert Level 4
Ive been buying this for a few years now, this works for my skin once in awhile , sometimes it will clear up the little pimples and sometimes it doesn't
Katie K.
Nashville, TN
82 reviews
Beauty Junkie Expert Level 2
I do not think Clean and Clear is a very effective brand. This particular product did nothing for my acne. I feel I wasted my money trying this brand.
Ryan K.
Malden, MA
44 reviews
Beauty Junkie Expert Level 2
I love this stuff! Very effective and helps fade pimples as well as acne scarring. It's one of the more expensive products in the line but works great
Lexy D.
Milford, OH
16 reviews
This SAVED my skin in high school and to this day (post college) I still reach for it. Cleans me right up in a day or two! Great price and great brand!
Karimi A.
Corp Christi, TX
95 reviews
Beauty Junkie Expert Level 2
Love love love this product when I have a random break out and need it cleared up for the next day. I have bought this product several times. My go to.
Melissa G.
Kunkletown, PA
10 reviews
This is the best spot treatment I've come across. It reduced the size and redness of any pimple I've gotten over night without over drying out my skin
Helena M.
Little Falls, NJ
16 reviews
Beauty Junkie Expert Level 1
This is fine feeling but I never noticed a difference from it. Not sure if it’s just my reaction to it or not, but I was disappointed with the results.
Ipo C.
Kekaha, HI
64 reviews
Beauty Junkie Expert Level 3
I used this in high school when I had really bad acne and super oily skin. It leaves my skin moisturized but not too oily and actually gets rid of acne
Daniella T.
Williamstown, NJ
246 reviews
Beauty Junkie Expert Level 4
Pretty decent spot treatment. It has salicylic acid in it which helps getting rid of your blemish faster. It seems gentle and doesn't over dry the area
Katie S.
Granville, IL
337 reviews
Beauty Junkie Expert Level 5
I bought this in a group with a three step process this being the third step and the process work amazing considering the set was $20. super impressed.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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