Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,717 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,720)
Q&A (493)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Katie K.
Nashville, TN
82 reviews
Beauty Junkie Expert Level 2
I do not think Clean and Clear is a very effective brand. This particular product did nothing for my acne. I feel I wasted my money trying this brand.
nicole g.
Everett, MA
496 reviews
Wasn't a fan of this product. I think Clyndamicyn and 10% Benzoyl Peroxide work much better. Those 2 products together clear up skin within 5-6 hours.
Ipo C.
Kekaha, HI
69 reviews
Beauty Junkie Expert Level 3
I used this in high school when I had really bad acne and super oily skin. It leaves my skin moisturized but not too oily and actually gets rid of acne
Delora D.
Columbus, OH
54 reviews
Beauty Junkie Expert Level 3
Clean & Clear Acne Advantage Spot Treatment is my favorite spot treatment for pop up acne. It definitely helps eliminate the time the acne is visible.
Lexy D.
Milford, OH
27 reviews
This SAVED my skin in high school and to this day (post college) I still reach for it. Cleans me right up in a day or two! Great price and great brand!
Amanda M.
Saint Paul, MN
68 reviews
Beauty Junkie Expert Level 2
It works well but it can sometimes leave a weird texture that pills up which i dont love and is hard to wear under makeup so i wear this only at night
allie c.
Granger, IN
93 reviews
Beauty Junkie Expert Level 2
love this spot treatment, i apply it as soon as i feel a pimple coming in and it reduces the size and redness of the pimple within the next day or two.
Kayleigh G.
Midway Park, NC
50 reviews
Beauty Junkie Expert Level 1
My number one go to spot treatment gel. This product dries out pimples over night! Cheap and effective! I am also able to find it at every drug store!
Samantha R.
Oxford, MA
15 reviews
I noticed a slight difference in my break outs when I used this but not anything drastic. It's okay, but I'm sure there is something better out there.!
Katie D.
Summit, MS
93 reviews
Its very effective in drying out and removing the redness when I get a pimple. First got it with they kit & I liked it so much I purchased this again.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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