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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,328 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10328)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Monica G.
Pooler, GA
47 reviews
Beauty Junkie Expert Level 3
This is a great little spot treatment to use overnight and it visibly reduces the size of a breakout which is a great thing to wake up to in the morning!
Krystle V.
Abington, PA
31 reviews
Beauty Junkie Expert Level 1
Worked like a charm. I could put it on at night and by morning my pimples looked smaller. It wasn't a thick cream either, it was light weight and clear.
Juliana O.
83 reviews
Beauty Junkie Expert Level 1
AMAZING if you are breaking out the day before something really important then just use the clean and clear advantage acne spot treatmeant it is amazing
Ashley G.
Tampa, FL
604 reviews
Beauty Junkie Expert Level 4
This acne spot treatment actually works wonders for what it costs. I was skeptical at first, but the first time I used it, it was a miracle in a bottle.
Rebecca B.
Pinellas Park, FL
20 reviews
Beauty Junkie Expert Level 3
This is my go to product when I get a blemish. It immediately dries it up and heals it. It may not be great for sensitive skin, but is amazing otherwise. 
Kristine B.
Somerville tx
46 reviews
Beauty Junkie Expert Level 3
I have prescribed stuff from a dermatologist and it's basically all the stuff that is in here so much cheaper it works just like a prescription one would
Brittany R.
141 reviews
This product is amazing. If you have a pimple pop up just cleanse your face and apply this to the acne and by the end of the day it's already shrinking.
Perla R.
Salt Lake City
6 reviews
Does what it’s supposed to do but it’s a slow process. I usually will leave this product on during the day when I’m not using my nightly acne treatment.
KieraJane x.
Richmond, VA
30 reviews
The ingredients used in the product really work on spots and I definitely give a thumbs up on this product. It burns on the spot, but for a good reason.
Chelsea P.
28 reviews
Beauty Junkie Expert Level 1
This is my go to spot treatment! Whenever I have a pimple pop up, I put this on and it's either gone or visibly smaller the next day. It's truly magical!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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