Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,756 Q&A

  • Does this product work?2 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,814)
Q&A (508)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
leanne g.
Chicago, IL
55 reviews
Beauty Junkie Expert Level 4
love using this when i feel a bump peeking through! shrinks acne tremendously. you can control the amount that comes out. you will feel a sting but if works!
Beatriz F.
Fort worth, TX
111 reviews
Beauty Junkie Expert Level 2
I love this for spot treatments. When I feel a painful pimple about to appear I dab a little of this over night and the next morning I can't feel it anymore.
Alexandra K.
Mount Airy, NC
113 reviews
Beauty Junkie Expert Level 3
Best spot treatment ever! I have used this in the past when I purchased the Clean and Clear Acne Treatment kit. Literally, vanishes imperfections overnight.
Elyse H.
Jeffersonvlle, IN
10 reviews
I use this every time I have a pimple pop up. Just put a dab on there a couple times a day and it quickly dries it out without completely drying out my skin.
Kelsey T.
Broken Arrow, OK
180 reviews
Beauty Junkie Expert Level 2
I love this product! I've used other than leave my face feels dry and tight where I use it, but this doesn't feel that way at all. It actually works for me.
Demi S.
Clearwater, FL
83 reviews
Beauty Junkie Expert Level 2
I get big, obnoxious, pimples on the worse days! This lightens and reduces it into completely nothing. A lot better than popping it and bleeding everywhere.
Natasha w.
246 reviews
Beauty Junkie Expert Level 3
I swear by this it helps my acne so much and reduces the redness. I really like this over other products because it isn't too harsh but it gets the job done
Mystye S.
Howell, MI
13 reviews
Beauty Junkie Expert Level 2
A little bit really goes a long way. Put this on acne spots everyday and in 2 days the marks will be gone. I love using this product and highly recommend it.
Jennie M.
Palmdale, CA
2 reviews
The best I've tried for stubborn acne areas, it can dry out your sky if you have sensitive/dry skin, but shrinks acne fast and makes a noticeable difference.
60 reviews
Beauty Junkie Expert Level 1
Are you does and every single routine that I use or maybe even if I feel that I’m having a break out but it really breaks down the blemish that I have on my
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

Influenster Cashback
We recorded your visit.
Clean & Clear® Advantage® Acne Spot Treatment

Amazon was opened in another window. If you made a purchase Cash Back will be automatically added to your Ebates account tomorrow.

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.