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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,321 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10321)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kyla M.
22 reviews
Beauty Junkie Expert Level 1
I have been using this product for awhile now, and let me tell you how amazing it is. My acne has cleared up so much since I started using this product!!!
Chana K.
Ft Lauderdale, FL
44 reviews
Beauty Junkie Expert Level 1
This product works well on small to mid sized acne/blemishes, however, if you have something large it's not as good. Typically takes 3 days to really heal.
Erin B.
60 reviews
Beauty Junkie Expert Level 1
This is a great product. Can wear it at night or during the day and people won't even notice!! Also helps get rid of those difficult pimples pretty quickly
Janine S.
White Plains, NY
258 reviews
Beauty Junkie Expert Level 4
This is great because i am allergic to benzoil peroxide (sp) and that ingredient is NOT in this product. instead they use salicydic acid. a great product
Jen R.
Broken Arrow, OK
61 reviews
Beauty Junkie Expert Level 4
I really like this acne treatment. It is perfect for very quick application. I use this at the first sign of acne and it typically clears it up by morning!
Brooke K.
Richmond, VA
58 reviews
Beauty Junkie Expert Level 1
I have not personally used this product my my boyfriend uses this religiously and it works for him. He has moderate acne so he uses it as a spot treatment.
Angeli B.
S Chesterfld, VA
60 reviews
Beauty Junkie Expert Level 2
Reasons why I don't like this product. First off it makes your pimple/zit 100* bigger. It also leave acne scars. I recommend not to purchase this product.
Suzi S.
Tina, MO
52 reviews
I know that the ingredients in this are supposed to work with acne, but I really don't find any difference when I use it. I find honey does a better job.
Zahra D.
267 reviews
Beauty Junkie Expert Level 4
Sometimes it works and sometimes it takes longer depending on the size of the pimple. I just keep applying all day long as long as I’m not wearing makeup.
Jessica H.
Oceanside, CA
64 reviews
I enjoy this product but it doesn't work for all my pimples. But works pretty well. I would try it at least once if you're looking for a spot treatment.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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