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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,305 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10305)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Leigh S.
Bradenton, FL
146 reviews
Beauty Junkie Expert Level 3
This is a great during the day spot treatment because it's clear and can be used under makeup. I do feel it speeds up the healing and removal of a pimple.
Taylor O.
Brewster, NY
29 reviews
Beauty Junkie Expert Level 1
I love this stuff it’s amazing. I use it when ever I get pimples. It’s harsh if u put it close to your eyes. I got it at ride aid. It wasn’t disappointing.
Benita C.
53 reviews
Beauty Junkie Expert Level 1
It definitely works but if you have sensitive skin try not to leave it on too long or go out in the sun with it on your face because it will start burning
Jennifer W.
Norfolk, VA
27 reviews
Beauty Junkie Expert Level 1
I usually can stretch a tube out fairly long as I don't have frequent breakouts.  When I do have to use it it clears up any issue within about 2 days!
Nikki P.
Odenville , AL
49 reviews
Beauty Junkie Expert Level 1
I dont struggle with acne, but i do get a few bumps here and there and this clears it up in no time, but u have not had a lot of experience with using it.
molly l.
12 reviews
i love this product!!! i've been using it for about a year and helps to minimize acne overnight! it doesn't dry out the skin either. 10/10 would reccomend
Leslie L.
Fort Smith
73 reviews
Beauty Junkie Expert Level 2
I didn’t get the immediate results a lot of people see. I used this several times and it didn’t seem to effect my acne, which is more cystic than topical.
Amanda S.
Bronx, NY
78 reviews
Beauty Junkie Expert Level 3
This product is not worth buying because it didn't really help my breakouts at all! The only thing it did was dry my skin but my acne stayed the exact same
Allisha O.
Chico, CA
43 reviews
Beauty Junkie Expert Level 1
This little guy is my secret weapon. If I catch a breakout early enough, this spot treatment clears it up within a few days. I just wish it worked faster!
tory s.
9 reviews
This is so much more gentle than other spot treatments without losing effectiveness. It never burns my skin after applying it like others have in the past.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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