Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #10 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,707)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Melissa D.
Charlotte , Nc
13 reviews
Best acne treatment I have ever used. I have used this for the past 2 years and anytime I get a pimple it always works. I haven't purchased any other acne treatment since using this.
Emily H.
254 reviews
This product has been able to get ride of or even diminish my pimples in just a few days or even over night! I have sensitive skin and it hasn't fried out my skin I have ever used it.
Kaytlyn W.
36 reviews
I've used this for years but recently it's stopped working for me. Not sure why. It had always been my preferred spot treatment of choice, but lately my skin doesn't react well to it.
Ashley G.
29 reviews
Beauty Junkie Expert Level 1
I didn't notice a difference after using this product. It felt harsh on my skin, but it didn't do the job. I wasn't impressed. I bought it at Walmart for a reasonable price, and I wouldn't recommend it to others.
Mariah H.
Modesto, CA
12 reviews
This spot treatment works so well. I use it constantly when I have pimples that make surprise visits and they are gone within a day or two. Love it and have been using it for years!
Chante P.
301 reviews
Beauty Junkie Expert Level 4
I started using this product right away when I could see a pimple starting to form and by the next day it was gone! This product works really well and I'm really glad that I bought it
Allison T.
Arlington, TX
32 reviews
Great spot treatment for the price, I do wish you got a little bit more in the tube but it does a really great job for those crazy huge zits that show up at 7 am and you need to get rid of them before tomorrow
Ashley W.
New Braunfels, TX
115 reviews
So far it really seems to be working. have had issues the past few months so hoping to help with acne as well as scarring. Bought yesterday and now it is on sale today...on'y downside
Genesis C.
New York, NY
39 reviews
This product may work for others but it did not work in the slightest for me. I didn't see any redness reduce or pimple size reduction. Maybe because I have severe acne with oily skin.
rikkeisha l.
Port Hadlock, WA
66 reviews
Beauty Junkie Expert Level 2
been using this stuff for years and it definitely helps with new acne scars. if you use it enough it tones your skin in the darker spots where you have older scars as well
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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